Sensitization with Eustrongylides sp. (Nematoda: Dioctophymatidae) antigens

Sensitization with Eustrongylides sp. (Nematoda: Dioctophymatidae) antigens induce manufacturing of particular IgG and IgE in murine mannequin 

Fish consumption performs an necessary position in human eating regimen. Hoplias malabaricus, generally often known as traíra, is a freshwater fish extensively appreciated in a number of Brazilian states and regularly contaminated by Eustrongylides sp. fourth-instar larvae (L4). The purpose of the current research was to guage allergenic potential of Eustrongylides sp. L4 crude extract (CEE). BALB/c mice had been immunized intraperitoneally (IP) by 10 μg CEE with 2 mg of aluminum hydroxide on days zero and 35. Particular IgG and IgE antibody ranges had been decided after immunization and mobile immunity was evaluated by assessing intradermal response in ear pavilion.

Epicutaneous sensitization was carried out in dorsal area by antigen publicity utilizing a Finn-type chamber containing 50 μg of CEE or saline answer, adopted by analysis of particular antibody ranges. IP immunization resulted in a gradual enhance in IgG antibody ranges and transitory IgE manufacturing. Vital enhance in ear thickness was noticed in mobile hypersensitivity response. In case of antigen publicity by epicutaneous route, CEE was in a position to induce meaningfully elevated ranges of particular IgG and IgE antibodies in addition to heightened mobile immunity. Each intraperitoneal immunization and epicutaneous contact with Eustrongylides sp. larval antigens had been noticed for first time to be able to inducing immunological sensitization in mice.

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Pig Anti SCL 70 antibody ELISA kit

E07S0243-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Anti SCL 70 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Anti SCL 70 antibody ELISA kit

E07S0243-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Anti SCL 70 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Anti SCL 70 antibody ELISA kit

E08S0243-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Anti SCL 70 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Anti SCL 70 antibody ELISA kit

E08S0243-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Anti SCL 70 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Anti SCL 70 antibody ELISA kit

E08S0243-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine Anti SCL 70 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Anti SCL 70 antibody ELISA kit

E02S0243-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Anti SCL 70 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Anti SCL 70 antibody ELISA kit

E02S0243-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Anti SCL 70 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Anti SCL 70 antibody ELISA kit

E02S0243-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Anti SCL 70 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Anti SCL 70 antibody ELISA kit

E06S0243-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat Anti SCL 70 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Anti SCL 70 antibody ELISA kit

E06S0243-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat Anti SCL 70 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Anti SCL 70 antibody ELISA kit

E06S0243-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat Anti SCL 70 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Anti SCL 70 antibody ELISA kit

E03S0243-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Anti SCL 70 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Anti SCL 70 antibody ELISA kit

E03S0243-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Anti SCL 70 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Anti SCL 70 antibody ELISA kit

E03S0243-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Anti SCL 70 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Anti SCL 70 antibody ELISA kit

E01S0243-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Anti SCL 70 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Anti SCL 70 antibody ELISA kit

E01S0243-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Anti SCL 70 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Anti SCL 70 antibody ELISA kit

E01S0243-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Anti SCL 70 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Anti SCL 70 antibody ELISA kit

E09S0243-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey Anti SCL 70 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Anti SCL 70 antibody ELISA kit

E09S0243-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey Anti SCL 70 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Anti SCL 70 antibody ELISA kit

E09S0243-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey Anti SCL 70 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Anti SCL 70 antibody ELISA kit

E04S0243-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit Anti SCL 70 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Anti SCL 70 antibody ELISA kit

E04S0243-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit Anti SCL 70 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Anti SCL 70 antibody ELISA kit

E04S0243-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit Anti SCL 70 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

DNA Topoisomerase I (TOP1, Scl-70) Antibody

30267-05111 150 ug
EUR 313.2

Rat Scl-70 Ab ELISA Kit

ERS0249 96Tests
EUR 625.2

Goat Scl-70 Ab ELISA Kit

EGTS0249 96Tests
EUR 625.2

Mouse Scl-70 Ab ELISA Kit

EMS0249 96Tests
EUR 625.2

Human Scl-70 Ab ELISA Kit

EHS0249 96Tests
EUR 625.2

Rabbit Scl-70 Ab ELISA Kit

ERTS0249 96Tests
EUR 625.2

Bovine Scl-70 Ab ELISA Kit

EBS0249 96Tests
EUR 625.2

Canine Scl-70 Ab ELISA Kit

ECS0249 96Tests
EUR 625.2

Porcine Scl-70 Ab ELISA Kit

EPS0249 96Tests
EUR 625.2

Anserini Scl-70 Ab ELISA Kit

EAS0249 96Tests
EUR 625.2

Guinea pig Anti SCL 70 antibody ELISA kit

E05S0243-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Guinea pig Anti SCL 70 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Anti SCL 70 antibody ELISA kit

E05S0243-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Guinea pig Anti SCL 70 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea pig Anti SCL 70 antibody ELISA kit

E05S0243-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Guinea pig Anti SCL 70 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Guinea Pig Scl-70 Ab ELISA Kit

EGS0249 96Tests
EUR 625.2

DNA Topoisomerase I (TOP1, Scl-70) Antibody (Biotin Conjugate)

30267-05121 150 ug
EUR 442.8

Mouse Anti-Hepatitis B Core Antigen (a.a. 70-80) Monoclonal Antibody

DMAB3506 0.1 mg
EUR 826.8

DNA Topoisomerase I (TOP1, Scl-70) AssayLite Antibody (RPE Conjugate)

30267-05151 150 ug
EUR 513.6

DNA Topoisomerase I (TOP1, Scl-70) AssayLite Antibody (APC Conjugate)

30267-05161 150 ug
EUR 513.6

DNA Topoisomerase I (TOP1, Scl-70) AssayLite Antibody (FITC Conjugate)

30267-05141 150 ug
EUR 513.6

DNA Topoisomerase I (TOP1, Scl-70) AssayLite Antibody (PerCP Conjugate)

30267-05171 150 ug
EUR 565.2

Cancer Antigen 242 Antigen

VAng-Cr3876-10kU 10 kU
EUR 505.2
Description: Cancer Antigen 242 Antigen, Host/Source: Metastatic Liver. The purity is detected by gel filtration.

Recombinant Plasmodium Falciparum PPF2L antigen Protein (aa 1-70)

VAng-Wyb6754-1mgBaculovirus 1 mg (Baculovirus)
EUR 8391.6
Description: Plasmodium Falciparum (isolate Palo Alto / Uganda) PPF2L antigen, recombinant protein.

Recombinant Plasmodium Falciparum PPF2L antigen Protein (aa 1-70)

VAng-Wyb6754-500gBaculovirus 500 µg (Baculovirus)
EUR 5388
Description: Plasmodium Falciparum (isolate Palo Alto / Uganda) PPF2L antigen, recombinant protein.

Recombinant Plasmodium Falciparum PPF2L antigen Protein (aa 1-70)

VAng-Wyb6754-50gBaculovirus 50 µg (Baculovirus)
EUR 2881.2
Description: Plasmodium Falciparum (isolate Palo Alto / Uganda) PPF2L antigen, recombinant protein.

Recombinant (sf9) Human Scl-70 protein (>95%, His-tag)

SCL702-R-10 10 ug
EUR 343.2

Human Scl-70 Autoantibody IgG ELISA Kit (Direct EIA)

EK7087 96wells/kit, with removable strips.
EUR 573.6

Recombinant (sf9) Human Scl-70 protein WB +ve control

SCL701-C 100 ul
EUR 343.2

Mouse Anti-Hepatitis C Virus Core Antigen (a.a. 70-90) Monoclonal Antibody

DMAB3561 0.1 mg
EUR 937.2

Cancer Antigen 50 Antigen

VAng-Cr3877-50kU 50 kU
EUR 6642
Description: Cancer Antigen 50 Antigen, Host/Source: Human Cell Culture. It is tested negative for HBsAg, antibodies to HCV and HIV 1/2.

Cancer Antigen 72-4 Antigen

VAng-Cr3878-10kU 10 kU
EUR 505.2
Description: Cancer Antigen 72-4 Antigen, Host/Source: Metastatic Liver. The purity is ~65% by SDS-PAGE. It is tested negative for HBsAg, antibodies to HCV and HIV 1/2.

Human Anti-Scl-70 (Scl70/Scleroderma 70 Kda/DNA-topoisomerase-1) IgG negative control serum/plasma

3300-140-N01 1 ml
EUR 196.8

Human Anti-Scl-70 (Scl70/Scleroderma 70 Kda/DNA-topoisomerase-1) IgG positive control serum/plasma

3300-140-P02 1 ml
EUR 270

Cancer Antigen 125 Antigen (Ascites Fluid)

VAng-Cr3870-10kU 10 kU
EUR 1132.8
Description: Cancer Antigen 125 Antigen, Host/Source: Ascites Fluid. The purity is ≥ 95% by SDS-PAGE.

Cancer Antigen 125 Antigen (Human Adenocarcinoma)

VAng-Cr3868-10kU 10 kU
EUR 505.2
Description: Cancer Antigen 125 Antigen, Host/Source: Human Adenocarcinoma. The purity is detected by salt extraction and chromatography.

Human carcinoembryonic antigen (CEA) antigen

CEA15-N-100 100 ug
EUR 270

Cancer Antigen CEA Antigen (Human Fluids)

VAng-Wyb8644-inquire inquire Ask for price
Description: Carcinoembryonic Antigen, Calibrator Grade, Cancer antigen from Human Fluids, 1.13 mg/mL.

Cancer Antigen 19-9 Antigen (Liver Carcinoma)

VAng-Cr3873-10kU 10 kU
EUR 472.8
Description: Cancer Antigen 19-9 Antigen, Host/Source: Liver Carcinoma. The purity is detected by gel filtration and ion-exchange chromatography. It is tested negative for HBsAg, antibodies to HCV and HIV 1/2.

Human Anti-Scl-70 (Scl70/Scleroderma 70 Kda/DNA-topoisomerase-1) IgG ELISA kit, 96 tests, Quantitative

3300-140-SCG 1 Kit
EUR 708

Prostate Specific Antigen Std Grade Antigen

VAng-Cr3891-1mg 1 mg
EUR 604.8
Description: Prostate Specific Antigen Std Grade Antigen, Host/Source: Human Seminal Fluid. The purity is detected by salt precipitation.

Cancer Antigen 125 Antigen (Human Adenocarcinoma) (> 90%)

VAng-Cr3869-25kU 25 kU
EUR 967.2
Description: Cancer Antigen 125 Antigen, Host/Source: Human Adenocarcinoma. The purity is> 90% by SDS-PAGE. Matched Pair: HM183, HM184, HM185, HM186.

HBV surface recombinant antigen HBsAg antigen

00123-V-01mg 0,1 mg
EUR 321
Description: HBV surface recombinant antigen HBsAg antigen 22 kDa Pichia pastoris recombinant High purity

HBV surface recombinant antigen HBsAg antigen

00123-V-1000ug 1000 ug
EUR 1539
Description: HBV surface recombinant antigen HBsAg antigen 22 kDa Pichia pastoris recombinant High purity

HBV surface recombinant antigen HBsAg antigen

00124-V-01mg 0,1 mg
EUR 321
Description: HBV surface recombinant antigen HBsAg antigen 31 kDa E. coli recombinant

HBV surface recombinant antigen HBsAg antigen

00124-V-1000ug 1000 ug
EUR 1539
Description: HBV surface recombinant antigen HBsAg antigen 31 kDa E. coli recombinant

Cancer Antigen 19-9 Antigen (Liver Carcinoma) (> 90%)

VAng-Cr3875-25kU 25 kU
EUR 885.6
Description: Cancer Antigen 19-9 Antigen, Host/Source: Liver Carcinoma. The purity is> 90% by SDS-PAGE. It is tested negative for HBsAg, antibodies to HCV and HIV 1/2.

Cancer Antigen AFP Antigen (Human Cord Blood)

VAng-Wyb8624-inquire inquire Ask for price
Description: Alpha Fetoprotein (66 kDa), Cancer antigen from Human Cord Blood, 1.73 mg/mL.

Cancer Antigen CA-125 Antigen (Human Fluids)

VAng-Wyb8639-inquire inquire Ask for price
Description: CA-125, Calibrator Grade, cancer antigen from Human Fluids, 53.26 KU/mL.

Cancer Antigen 15-3 MUC 1 Antigen (Human Milk)

VAng-Cr3871-10kU 10 kU
EUR 505.2
Description: Cancer Antigen 15-3 MUC 1 Antigen, Host/Source: Human Milk. The purity is detected by salt extraction and delipidization following high speed centrifugation. It is tested negative for HBsAg, antibodies to HCV and HIV 1/2.

CD9 Antigen

E6TA00101 0.1mg
EUR 411.6

MPO Antigen

E61A00501 1mg
EUR 1230

HAV Antigen

E61H00101 1mg
EUR 733.2

HBS Antigen

E61H00301 1mg
EUR 374.4

HBS Antigen

E61H00302 1mg
EUR 374.4

HBe Antigen

E61H00501 1mg
EUR 463.2

HBc Antigen

E61H00701 1mg
EUR 463.2

AFP Antigen

E62C002 20ug
EUR 458.4

HCG Antigen

E62C004 100ug
EUR 458.4

CEA Antigen

E62C010 20ug
EUR 458.4

CK8 Antigen

E62C02001 20ug
EUR 458.4

CRP Antigen

E64C00501 1mg
EUR 840

CRP Antigen

E64C00502 1mg
EUR 840

BSA Antigen

IM112 1 ml
EUR 342
Description: BSA Antigen by Cygnus Technologies is available in Europe via Gentaur.

HSA Antigen

IM118 1 ml
EUR 342
Description: HSA Antigen by Cygnus Technologies is available in Europe via Gentaur.

CDV Antigen

VAng-Lsx0016-1mg 1 mg
EUR 1688.4
Description: Canine Distemper Virus Antigen from SL-29 cells.

Gastrointestinal Cancer Antigen (CA 19-9), antigen grade

CA1991-N-10 10 KU
EUR 634.8

Cancer Antigen CEA Antigen (Human Metastatic Liver)

VAng-Wyb8645-inquire inquire Ask for price
Description: Carcinoembryonic Antigen, Antigen Grade, Cancer antigen from Human Metastatic Liver, 5.5 mg/mL.

CD63 Antigen

E6TA00102 0.1mg
EUR 411.6

CD81 Antigen

E6TA00103 0.1mg
EUR 411.6

S100 Antigen

E62B003 20ug
EUR 458.4

CA50 Antigen

E62C009 10KU
EUR 458.4

CK18 Antigen

E62C02101 20ug
EUR 458.4

CK20 Antigen

E62C02201 20ug
EUR 458.4

GP73 antigen

E62C02701 20ug
EUR 458.4

TP17 Antigen

E62H00701 100ug
EUR 458.4

TP47 Antigen

E62H00702 100ug
EUR 458.4

cTnI antigen

E64C00101 100ug
EUR 508.8

cTnI antigen

E64C00102 100ug
EUR 733.2

cTnC antigen

E64C01301a 20ug
EUR 411.6

sST2 antigen

E64C01501 20ug
EUR 411.6

PAPP Antigen

E64D00101 100ug
EUR 1425.6

PAPP Antigen

E64D00102 1mg
EUR 5910

HSP70 Antigen

E6TA00104 0.1mg
EUR 411.6

CD133 Antigen

E6TA00105 0.1mg
EUR 411.6

CD32a Antigen

E6TA00106 0.1mg
EUR 411.6

CA242 Antigen

E62C00601 50KU
EUR 2078.4

CA242 Antigen

E62C00602 10KU
EUR 458.4

CA199 Antigen

E62C007 10KU
EUR 458.4

CA199 Antigen

E62C00701 50KU
EUR 1180.8

CA199 Antigen

E62C00702 50KU
EUR 1620

CA125 Antigen

E62C011 10KU
EUR 458.4

CA153 Antigen

E62C012 10KU
EUR 458.4

EpCAM Antigen

E64B00107 0.1mg
EUR 411.6

Cancer Antigen CA-125 Antigen (Human Adenocarcinoma)

VAng-Wyb8642-inquire inquire Ask for price
Description: CA-125, Calibrator Grade, Cancer antigen from Human Adenocarcinoma, 500 kIU / mL.

S100BB Antigen

E62B00201 20ug
EUR 458.4

S100BB Antigen

E62B00202 20ug
EUR 458.4

Giardia Trophozoite Recombinant antigen antigen 34 kDa

00321-V-01mg 0,1 mg
EUR 321
Description: Giardia Trophozoite Recombinant antigen antigen 34 kDa a.a. 21-280

Giardia Trophozoite Recombinant antigen antigen 34 kDa

00321-V-1000ug 1000 ug
EUR 1539
Description: Giardia Trophozoite Recombinant antigen antigen 34 kDa a.a. 21-280

Cancer Antigen 19-9 Antigen (Liver Carcinoma) (High purity)

VAng-Cr3874-25kU 25 kU
EUR 1033.2
Description: Cancer Antigen 19-9 Antigen, Host/Source: Liver Carcinoma.

Positive Control Set (SS-A, SS-B, Sm, RNP, Scl-70, Jo-1) Antibody

abx022694-1Set 1 Set
EUR 1696.8

S100A1B Antigen

E62B00101 20ug
EUR 458.4

S100A1B Antigen

E62B00102 20ug
EUR 458.4

Insulin Antigen

E64I001 1mg
EUR 418.8

Insulin Antigen

IM121 1 ml
EUR 342
Description: Insulin Antigen by Cygnus Technologies is available in Europe via Gentaur.

Ferritin Antigen

E62C013 100ug
EUR 458.4

Ferritin Antigen

E62C01304 100ug
EUR 458.4

Copeptin antigen

E64C01601 100ug
EUR 411.6

Cancer Antigen AFP Antigen (Human hepatocellular carcinoma)

VAng-Wyb8625-inquire inquire Ask for price
Description: Alpha Fetoprotein, Antigen Grade, Cancer antigen from human hepatocellular carcinoma, 2.93 mg/mL.

Rotavirus Antigen

DAGA-258 1 ml dry ice
EUR 873.6

Cancer Antigen 15-3 MUC 1 Antigen (Human Ascites Fluid)

VAng-Cr3872-10kU 10 kU
EUR 1363.2
Description: Cancer Antigen 15-3 MUC 1 Antigen, Host/Source: Human Ascites Fluid.

Enterovirus Antigen

30-1984 1 mg
EUR 855.6
Description: Enterovirus Protein

Hydrocodone Antigen

VAng-Cr3693-1mg 1 mg
EUR 967.2
Description: Hydrocodone Antigen, matched pairs: JP101, JP102 or JP103 (detection); Used for ELISA, Lateral Flow.

RV Antigen (E1)

E61Y00101 1mg
EUR 840

Calprotectin Antigen

DAG-T1230 1mg
EUR 4446

IL-2 antigen

E6IE600106 20ug
EUR 411.6

IL-4 antigen

E6IE600107 20ug
EUR 411.6

IL-6 antigen

E6IE600108 20ug
EUR 411.6

IL-2 antigen

E6L00106 20ug
EUR 458.4

IL-4 antigen

E6L00107 20ug
EUR 458.4

IL-6 antigen

E6L00108 20ug
EUR 458.4

SS-A Antigen

E61A00301 1mg
EUR 1230

SS-B Antigen

E61A00401 1mg
EUR 1230

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC470228-100 100uL
EUR 238.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF647 conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC470228-500 500uL
EUR 652.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF647 conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC550228-100 100uL
EUR 238.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF555 conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC550228-500 500uL
EUR 652.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF555 conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC400228-100 100uL
EUR 238.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF640R conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC400228-500 500uL
EUR 652.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF640R conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC430228-100 100uL
EUR 238.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF543 conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC430228-500 500uL
EUR 652.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF543 conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC810228-100 100uL
EUR 238.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF680R conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC810228-500 500uL
EUR 652.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF680R conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC610228-100 100uL
EUR 238.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF660R conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNC610228-500 500uL
EUR 652.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),CF660R conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNUM0228-50 50uL
EUR 474
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6), 1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNCB0228-100 100uL
EUR 238.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),Biotin conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNCB0228-500 500uL
EUR 652.8
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),Biotin conjugate, Concentration: 0.1mg/mL

HL-60 Antigen / Human Leukemia Antigen (IPO-M6) Antibody

BNCP0228-250 250uL
EUR 459.6
Description: Primary antibody against HL-60 Antigen / Human Leukemia Antigen (IPO-M6),PerCP conjugate, Concentration: 0.1mg/mL

Most cancers/Testis Antigens: from Serology to mRNA Most cancers Vaccine 

Most cancers/testis antigens (CTAs) are a gaggle of tumor antigens expressed in quite a few most cancers tissues, in addition to within the testis and placental tissues. There are over 200 CTAs supported by serology and expression information. The expression patterns of CTAs replicate the similarities between the processes of gametogenesis and tumorigenesis. It’s notable that CTAs are extremely expressed in three kinds of cancers (lung most cancers, bladder most cancers, and pores and skin most cancers), all of which have a metallic etiology.

Right here, we assessment the expression, regulation, and performance of CTAs and their translational prospects as most cancers biomarkers and remedy targets. Many CTAs are extremely immunogenic, tissue-specific, and regularly expressed in most cancers tissues however not underneath physiological circumstances, rendering them promising candidates for most cancers detection. Some CTAs are related to medical outcomes, so they might function prognostic biomarkers. A small variety of CTAs are membrane-bound, making them very best targets for chimeric antigen receptor (CAR) T cells. Mounting proof means that CTAs induce humoral or mobile immune responses, offering most cancers immunotherapeutic alternatives for T-cell receptors (TCRs), CAR T cell, antibody-primarily based remedy and peptide- or mRNA-based vaccines. Certainly, CTAs are the dominating non-mutated targets in mRNA most cancers vaccine growth.

Medical trials on CTA TCR and vaccines have proven effectiveness, security, and tolerance, however these successes are restricted to a small variety of sufferers. In-depth research on CTA expression and performance are wanted to enhance CTA-based immunotherapy.

Chimeric Antigen Receptor T Cell Remedy: A Complete Overview of Medical Efficacy, Toxicity, and Greatest Practices for Outpatient Administration 

Chimeric antigen receptor T cell (CAR-T) remedy has been built-in into remedy algorithms for acute leukemia and lymphoma, and the variety of medical trials in each hematologic and stable tumor malignancies for brand spanking new merchandise and potential indications continues to develop. The medical toxicities of CAR-T remedy embrace cytokine launch syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS), which usually warrant inpatient admission for shut monitoring and remedy. Consequently, many facilities have constructed processes round administration of those cells within the inpatient setting. As new merchandise achieve Meals and Drug Administration approval with extra manageable toxicity profiles, and as establishments achieve expertise with the administration of those toxicities, outpatient administration and monitoring must be anticipated.

As well as, payer reimbursements for inpatient remedy have left the sustainability of inpatient CAR-T remedy in jeopardy, particularly for facilities whose payer combine features a excessive proportion of Medicare sufferers. This has the intense potential to restrict entry to care. As use of CAR-T remedy continues to develop, adjustments in fee fashions, care settings, or each are wanted to make sure the sustainability of secure, environment friendly, and cost-effective remedy. This assessment outlines the efficacy and toxicity of at the moment accredited merchandise in addition to greatest practices to optimize the administration of CAR-T remedy within the outpatient setting.

IFCC interim tips on fast point-of-care antigen testing for SARS-CoV-2 detection in asymptomatic and symptomatic people 

With an virtually unremittent development of extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections all world wide, there’s a compelling must introduce fast, dependable, and high-throughput testing to permit acceptable medical administration and/or well timed isolation of contaminated people. Though nucleic acid amplification testing (NAAT) stays the gold customary for detecting and theoretically quantifying SARS-CoV-2 mRNA in numerous specimen sorts, antigen assays could also be thought-about an acceptable various, underneath particular circumstances.

Speedy antigen checks are supposed to detect viral antigen proteins in organic specimens (e.g. nasal, nasopharyngeal, saliva), to point present SARS-CoV-2 an infection. The obtainable assay methodology contains fast chromatographic immunoassays, used on the point-of-care, which carries some benefits and disadvantages in comparison with extra standard, instrumentation-based, laboratory immunoassays.

Due to this fact, this doc by the Worldwide Federation for Medical Chemistry and Laboratory Medication (IFCC) Taskforce on COVID-19 goals to summarize obtainable information on the efficiency of at the moment obtainable SARS-CoV-2 antigen fast detection checks (Ag-RDTs), offering interim steering on medical indications and goal populations, assay choice, and analysis, check interpretation and limitations, in addition to on pre-analytical concerns. This doc is therefore primarily aimed to help laboratory and controlled well being professionals in choosing, validating, and implementing regulatory accredited Ag-RDTs.

Chemotherapy brokers stimulate dendritic cells towards human colon most cancers cells by upregulation of the transporter related to antigen processing 

Single immunotherapy fails to reveal efficacy in sufferers with microsatellite steady (MSS) metastatic colorectal most cancers (mCRC). Analysis on immune reactions earlier than and after systemic brokers for mCRC is warranted. Our research examined cell line fashions to match the expression of immune floor markers on colon most cancers cells earlier than and after chemotherapy brokers. We additionally elucidated mechanisms underlying the results of chemotherapy brokers on immune floor markers. We used real-world medical samples with NanoString evaluation and the Perkin-Elmer Opal multiplex system. We established that chemotherapy brokers, notably 7-ethyl-10-hydroxycamptothecin (SN-38), the energetic metabolite of irinotecan, stimulated the expression of stimulatory MHC class I alleles by stimulation the pathway of transporters related to antigen processing 1 and a couple of (TAP1 and TAP2) in cell line fashions.

Utility of contaminated cell protein 47 (ICP-47), a selected inhibitor of the TAP1/TAP2, considerably inhibited expression of TAP1/TAP2 and likewise inhibited the expression of the downstream MHC class I. Within the practical assay, SN-38 considerably promoted the phagocytosis of colon most cancers cells by monocyte-derived dendritic cells (MoDCs). We confirmed that the expression of main histocompatibility complicated (MHC) class I, considerably elevated after first-line chemotherapy and focused remedy within the samples of real-world sufferers with de novo mCRC. Our research supplies new insights for novel immunotherapy mixtures.

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