Validation of the Effectiveness of Neutrophil

Validation of the Effectiveness of Neutrophil-to-lymphocyte Ratio (NLR) as a Predictive Consider Sufferers Present process Prostate Biopsy With Prostate Particular Antigen (PSA) Between 4.zero and 10.zero ng/ml

Background/goal: This examine aimed to entry the effectiveness of serum neutrophil-to-lymphocyte ratio (NLR) in sufferers present process prostate needle biopsy with a prostate particular antigen (PSA) between 4.zero and 10.zero ng/ml.

Sufferers and strategies: A complete of 633 circumstances had been eligible. We evaluated a number of components together with age, PSA, PSA-density (PSAD), platelet-to-lymphocyte ratio (PLR) and NLR within the presence or absence of prostate most cancers (PCa), retrospectively. We evaluated statistically the associations between every issue and pathological findings or Gleason rating.

Outcomes: A complete of 201 had been evaluated on this examine. Relating to the presence or absence of prostate most cancers, there have been statistically vital variations in age, PSA ranges, PSAD, the PLR and NLR. The imply NLR worth of the sufferers with PCa was considerably decrease in comparison with your entire cohort. Multivariate evaluation confirmed that age, PSAD, and NLR had been impartial danger components predicting PCa.

Conclusion: For sufferers having a PSA between 4.zero and 10.zero ng/ml, NLR was a predicting issue of PCa previous to prostate needle biopsy and an efficient biomarker and useful gizmo for avoiding pointless biopsies.

jointsjournal
jointsjournal
DiscoveryProbe? Stem Cell Compound Library
L1040-.1 100 uL/well(10 mM solution)
EUR 4353
Stem Cell MicroRNA Profiling Panel
RA620A-1 10 profiles
EUR 1172
  • Category: MicroRNA Tools
Mouse Stem Cell Factor (SCF) AssayMax ELISA Kit
EMS1001-1 96 Well Plate
EUR 396
Mouse Nanog Stem Cell Differentiation Reporter (pGreenZeo, plasmid)
SR10031PA-1 10 ug
EUR 1749
  • Category: Stem Cell Products
Mouse Nanog Stem Cell Differentiation Reporter (pGreenZeo, pre-packaged)
SR10031VA-1 >2 x 10^6 IFUs
EUR 755
  • Category: Stem Cell Products
Polyclonal Goat anti-GST α-form
GST-ANTI-1 50 uL
EUR 280
SCF Stem Cell Factor Human Recombinant Protein
PROTP21583-1 Regular: 10ug
EUR 317
Description: Stem Cell Factor Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 165 amino acids and having a molecular mass of 18409 Dalton. ;The SCF is purified by proprietary chromatographic techniques.
StemBoost? Neural Stem Cell Reprogramming Cocktail (100X)
S238-1
EUR 185
SCA-1 Antibody
47996-100ul 100ul
EUR 333
SCA-1 Antibody
47996-50ul 50ul
EUR 239
Human Stem Cell Factor (SCF) AssayMax ELISA Kit
ES1001-1 96 Well Plate
EUR 396
SCA-1 Conjugated Antibody
C47996 100ul
EUR 397
Mouse Prostate stem cell antigen (Psca)
1-CSB-YP018840MO
  • EUR 504.00
  • EUR 265.00
  • EUR 1832.00
  • EUR 763.00
  • EUR 1216.00
  • EUR 334.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 10.4 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Mouse Prostate stem cell antigen(Psca) expressed in Yeast
Anti-Periphilin 1 Antibody
A06996-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Periphilin 1 Antibody (PPHLN1) detection.tested for WB in Human, Mouse.
Anti-Lyl-1 Antibody
A07491-1 100ul
EUR 397
Description: Rabbit Polyclonal Lyl-1 Antibody. Validated in IHC and tested in Human, Mouse, Rat.
Anti-GLI-1 Antibody
A07972-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for GLI-1 Antibody (ACSS1) detection. Tested with WB in Human, Mouse, Rat.
Anti-Cerebellin 1 Antibody
A09176-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Cerebellin 1 Antibody (CBLN1) detection. Tested with WB in Human, Mouse, Rat.
Anti-DOC-1 Antibody
A09467-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for DOC-1 Antibody (CDK2AP1) detection. Tested with WB in Human, Mouse.
Anti-NPDC-1 Antibody
A12846-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for NPDC-1 Antibody (NPDC1) detection. Tested with WB in Human, Mouse, Rat.
Anti-CNG-1 Antibody
A05494-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for CNG-1 Antibody (CNGA1) detection. Tested with WB in Human, Mouse, Rat.
Anti-Flk-1 Antibody
A00901-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Flk-1 Antibody (KDR) detection.tested for WB in Human, Mouse.
Anti-EDG-1 Antibody
A01502-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for EDG-1 Antibody (S1PR1) detection.tested for WB in Human, Mouse, Rat.
Anti-ROBO-1 Antibody
A01530-1 100ug
EUR 455
Description: Rabbit Polyclonal ROBO-1 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.
Anti-Bag-1 Antibody
A02423-1 50 ul
EUR 397
Description: Rabbit Polyclonal Bag-1 Antibody. Validated in IP, IHC and tested in Bovine, Canine, Human, Mouse, Rat.
Anti-TUB 1 Antibody
A02917-1 100ug/vial
EUR 294
Anti-Dok-1 Antibody
A03039-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Dok-1 Antibody (DOK1) detection.tested for WB in Human, Mouse, Rat.
Anti-TFIIIB90-1 Antibody
A03761-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for TFIIIB90-1 Antibody (BRF1) detection.tested for WB in Human, Mouse.
Anti-Atrophin-1 Antibody
A03828-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Atrophin-1 Antibody (ATN1) detection. Tested with WB in Human, Mouse, Rat.
Anti-PARP-1 Antibody
A00122-1 100ul
EUR 397
Description: Rabbit Polyclonal PARP-1 Antibody. Validated in ELISA, IP, IF, WB and tested in Human, Mouse.
Anti-Presenilin 1 Antibody
A00138-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Presenilin 1 Antibody (PSEN1) detection. Tested with WB, IHC in Human, Mouse, Rat.
Anti-PAI-1 Antibody
A00637-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for PAI-1 Antibody (SERPINE1) detection.tested for WB in Human, Mouse, Rat.
Anti-HO-1 Monoclonal Antibody (HO-1-2)
M00253-1 1mg
EUR 397
Description: Mouse Monoclonal HO-1 Antibody (HO-1-2). Validated in Flow Cytometry, IHC, WB and tested in Human, Mouse, Rat.
Anti-Pyrophosphatase 1/PPA1 Antibody
A07485-1 100ug/vial
EUR 334
Anti-TCP-1 eta Antibody
A08169-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for TCP-1 eta Antibody (CCT7) detection. Tested with WB in Human, Mouse, Rat.
Anti-Relaxin 1/RLN1 Antibody
A08367-1 100ug/vial
EUR 334
Anti-TCP-1 zeta Antibody
A09373-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for TCP-1 zeta Antibody (CCT6A) detection.tested for WB in Human, Mouse, Rat.
Anti-CHST8/Galnac4St 1 Antibody
A10989-1 100ul
EUR 397
Description: Rabbit Polyclonal CHST8/Galnac4St 1 Antibody. Validated in WB and tested in Human, Mouse, Rat.
Anti-Musashi 1/Msi1 Antibody
A05052-1 100ug/vial
EUR 334
Anti-LOX-1/OLR1 Antibody
A00760-1 100ug/vial
EUR 294
Anti-Syndecan-1/SDC1 Antibody
A00991-1 100ug/vial
EUR 294
Anti-IRAK-1/IRAK1 Antibody
A01021-1 100ug/vial
EUR 334
Anti-Neurexin 1/NRXN1 Antibody
A01490-1 100ug/vial
EUR 334
Anti-Hexokinase 1/HK1 Antibody
A01504-1 100ug/vial
EUR 334
Anti-Synaptotagmin 1/SYT1 Antibody
A02314-1 100ug/vial
EUR 334
Anti-Syntenin-1 Monoclonal Antibody
A02475-1 100ul
EUR 397
Description: Mouse Monoclonal Antibody for Syntenin-1 Antibody (SDCBP) detection. Tested with WB in Human, Rat, Dog, Pig.
Anti-Dsg1/Desmoglein 1 Antibody
A02655-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Dsg1 Antibody (DSG1) detection.tested for IHC, WB in Human, Mouse, Rat.
Anti-CAF-1 p150 Antibody
A02732-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for CAF-1 p150 Antibody (CHAF1A) detection. Tested with WB in Human, Mouse.
Anti-Talin 1/TLN1 Antibody
A02859-1 100ug/vial
EUR 334
Anti-Islet 1/ISL1 Antibody
A02969-1 100ug/vial
EUR 334
Anti-TNF Receptor 1 Antibody
A00294-1 200ug
EUR 522
Description: Rabbit Polyclonal TNF Receptor 1 Antibody. Validated in IP, IHC, WB and tested in Human, Mouse, Rat.
Anti-Galectin 1/Lgals1 Antibody
A00470-1 100ug/vial
EUR 334
Anti-Angiopoietin 1/ANGPT1 Antibody
PA1333-1 100ug/vial
EUR 334
Anti-Presenilin 1 Monoclonal Antibody
M00138-1 100ug
EUR 397
Description: Rabbit Monoclonal Presenilin 1 Antibody. Validated in WB and tested in Human, Mouse, Rat.
Anti-Galectin 1 Monoclonal Antibody
M00470-1 100ug
EUR 397
Description: Rabbit Monoclonal Galectin 1 Antibody. Validated in IP, IF, WB and tested in Human, Mouse, Rat.
Anti-DJ-1 Monoclonal Antibody
M00757-1 100ul
EUR 397
Description: Mouse Monoclonal DJ-1 Antibody. Validated in IHC, WB and tested in Bovine, Human.
Anti-Enolase 1 Monoclonal Antibody
M01250-1 100ul
EUR 397
Description: Anti-Enolase 1 Monoclonal Antibody tested in WB, IF, ICC, IHC, reactive to Human, rat, mouse, cow, pig, horse
Anti-Dynamin 1 Monoclonal Antibody
M02536-1 100ug
EUR 397
Description: Rabbit Monoclonal Dynamin 1 Antibody. Validated in IF, WB and tested in Human, Mouse, Rat.
Anti-Esrp-1 Monoclonal Antibody
M06068-1 100uL
EUR 443
Description: Mouse Monoclonal Esrp-1 Antibody. Validated in WB and tested in Human.
Anti-Galectin 1/LGALS1 Antibody
PB9240-1 100ug/vial
EUR 334
CF350 Goat Anti-Mouse IgG1 (γ1), 2mg/mL
20245-1 50uL
EUR 149
Description: Minimum order quantity: 1 unit of 50uL
CF488A Goat Anti-Mouse IgG1 (γ1), 2mg/mL
20246-1 50uL
EUR 149
Description: Minimum order quantity: 1 unit of 50uL
CF555 Goat Anti-Mouse IgG1 (γ1), 2mg/mL
20247-1 50uL
EUR 149
Description: Minimum order quantity: 1 unit of 50uL
CF568 Goat Anti-Mouse IgG1 (γ1), 2mg/mL
20248-1 50uL
EUR 149
Description: Minimum order quantity: 1 unit of 50uL
CF594 Goat Anti-Mouse IgG1 (γ1), 2mg/mL
20249-1 50uL
EUR 149
Description: Minimum order quantity: 1 unit of 50uL
CF633 Goat Anti-Mouse IgG1 (γ1), 2mg/mL
20250-1 50uL
EUR 149
Description: Minimum order quantity: 1 unit of 50uL
CF640R Goat Anti-Mouse IgG1 (γ1), 2mg/mL
20251-1 50uL
EUR 149
Description: Minimum order quantity: 1 unit of 50uL
CF647 Goat Anti-Mouse IgG1 (γ1), 2mg/mL
20252-1 50uL
EUR 149
Description: Minimum order quantity: 1 unit of 50uL
CF680 Goat Anti-Mouse IgG1 (γ1), 2mg/mL
20253-1 50uL
EUR 161
Description: Minimum order quantity: 1 unit of 50uL
CF770 Goat Anti-Mouse IgG1 (γ1), 2mg/mL
20254-1 50uL
EUR 161
Description: Minimum order quantity: 1 unit of 50uL
CF543 Goat Anti-Mouse IgG1 (γ1), 2mg/mL
20325-1 50uL
EUR 149
Description: Minimum order quantity: 1 unit of 50uL
Prostate Stem Cell Antigen Antibody
33476-100ul 100ul
EUR 252
Prostate Stem Cell Antigen Antibody
33476-50ul 50ul
EUR 187
Prostate Stem Cell Antigen Antibody
DF8709 200ul
EUR 304
Description: Prostate Stem Cell Antigen Antibody detects endogenous levels of total Prostate Stem Cell Antigen.
Prostate Stem Cell Antigen Antibody
ABD8709 100 ug
EUR 438
Hemokinin 1 (mouse)
B5127-1 1 mg
EUR 321
AXMIR-1 RNA oligo anti-miRNA-1-3p with Xmotif
AXMIR-1 10 reactions
EUR 438
  • Category: Exosome
Anti-BOB-1/OBF-1 Rabbit Monoclonal Antibody, Clone#RM378
M04431-1 100uL
EUR 385
Description: Anti-BOB-1/OBF-1 Rabbit Monoclonal Antibody, Clone#RM378 tested in WB, IHC, reactive to Human
Anti-CELSR3/Flamingo Homolog 1 Antibody
A07204-1 100ul
EUR 397
Description: Rabbit Polyclonal CELSR3/Flamingo Homolog 1 Antibody. Validated in IF and tested in Human, Mouse, Rat.
Anti-LPCAT2/Acyltransferase Like 1 Antibody
A07471-1 100ul
EUR 397
Description: Rabbit Polyclonal LPCAT2/Acyltransferase Like 1 Antibody. Validated in WB and tested in Human, Mouse, Rat.
Anti-Hyaluronan synthase 1/HAS1 Antibody
A04784-1 100ug/vial
EUR 334
Anti-Liver Carboxylesterase 1/CES1 Antibody
A01741-1 100ug/vial
EUR 334
Anti-EBP50/NHERF-1/SLC9A3R1 Antibody
A02427-1 100ug/vial
EUR 334
Anti-IL1R2/Il 1 Rii Antibody
A03106-1 1 ml
EUR 397
Description: Rabbit Polyclonal IL1R2/Il 1 Rii Antibody. Validated in IP, WB and tested in Human.
Anti-HIF-1 alpha/HIF1A Antibody
A00013-1 100ug/vial
EUR 294
Anti-Cleaved-Notch 1 (V1754) Antibody
A00033-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Cleaved-Notch 1 (V1754) Antibody (NOTCH1) detection.tested for WB in Human, Mouse, Rat.
Anti-HDAC-1 (C-terminus) Antibody
A00256-1 100uL
EUR 443
Description: Rabbit Polyclonal HDAC-1 (C-terminus) Antibody. Validated in IF, IHC, WB and tested in Human.
Anti-VEGF Receptor 1/FLT1 Antibody
A00534-1 100ug/vial
EUR 294
Anti-Integrin alpha 1/ITGA1 Antibody
PA1045-1 100ug/vial
EUR 334
Anti-Caspase-1(P20)/CASP1 Antibody
PA1440-1 100ug/vial
EUR 294
Anti-VEGF Receptor 1/FLT1 Antibody
PA1966-1 100ug/vial
EUR 294
Anti-Sumo 1 Rabbit Monoclonal Antibody
M00631-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Sumo 1 Antibody. Validated in IP, IF, IHC, WB and tested in Human, Mouse, Rat.
Anti-Cytokeratin 1 Rabbit Monoclonal Antibody
M01639-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Cytokeratin 1 Antibody. Validated in WB and tested in Human, Mouse, Rat.
Anti-Mitofusin 1 Antibody (monoclonal, 3H3)
M02172-1 100ug/vial
EUR 294
Anti-Phospho-Beclin-1 (Ser295) Antibody
P00327-1 100ul
EUR 398
Description: Rabbit Polyclonal Phospho-Beclin-1 (Ser295) Antibody. Validated in WB and tested in Human.
Anti-Phospho-Raf-1 (Ser642) Antibody
P00446-1 100ul
EUR 398
Description: Rabbit Polyclonal Phospho-Raf-1 (Ser642) Antibody. Validated in WB and tested in Human, Rat.
TINAGL1 Human, Tubulointerstitial Nephritis Antigen Like 1 Human Recombinant Protein, Sf9
PROTQ9GZM7-1 Regular: 5ug
EUR 317
Description: TINAGL1 Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 455 amino acids (22-467a.a.) and having a molecular mass of 51.2kDa (Molecular size on SDS-PAGE will appear at approximately 50-70kDa). TINAGL1 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Anti-TTF-1
DB-089-1 1 ml
EUR 750
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated
Podocalyxin (PODXL) (Hematopoietic Stem Cell Marker); Clone 3D3 (Concentrate)
RA0264-C.1 0.1 ml
EUR 125

[Preparation of a novel tri-specific T cell engager targeting CD19 antigen and its anti-leukemia effect exploration] 

Goal: To arrange a novel tri-specific T cell engager (19TriTE) concentrating on CD19 antigen, and to analyze its immunotherapeutic impact on CD19-positive hematological malignancies.

Strategies: 19TriTE was constructed by molecular cloning know-how and efficiently expressed via the eukaryotic expressing system. The results of 19TriTE on the proliferation and activation of T cells, in addition to the particular cytotoxicity in opposition to CD19 constructive tumor cell strains had been verified.

Outcomes: ①19TriTE expressing plasmid was constructed and efficiently expressed via the eukaryotic expressing system. ②19TriTE can particularly bind to T cells and Nalm6 cells, with equilibrium dissociation constants of 19.21 nmol/L and 11.67 nmol/L, respectively. ③The expression charges of CD69 constructive T cells and CD25 constructive T cells had been 35.4% and 49.8% respectively, when 2 nmol/L 19TriTE had been added within the co-culture system, which had been considerably greater than these within the management group. ④19TriTE can considerably promote the proliferation of T cells.

Absolutely the depend of T cells expanded from the preliminary a million to 74 million with an 74 fold enhance on the focus of 1 nmol/L on day 12. ⑤19TriTE can considerably mediate T cells killing of CD19 constructive goal cells in a dose-dependent method. On the focus of 10 nmol/L, the goal cells lysis reached 50%. ⑥Degranulation experiment verified that 19TriTE can activate T cells within the presence of CD19 constructive goal cells, and the activation of T cells positively correlated with the dose of 19TriTE. ⑦When 19TriTE fusion protein co-cultured with T cells and goal cells overexpression RFP and luciferase genes respectively, 19TriTE can notably mediate T cells killing of CD19 constructive goal cells via fluorescent microscope or bioluminescence imaging know-how.

Conclusion: On this examine, we efficiently constructed and expressed 19TriTE fusion protein and verified that it could possibly successfully activate T cells and promote their proliferation in vitro. On the similar time, it could possibly bind to CD19 constructive goal cells and T cells, in addition to improve T cells anti-leukemia impact in vitro, offering the inspiration for additional scientific analysis.

Nanoparticles Displaying Allergen and Siglec-Eight Ligands Suppress IgE-FcεRI-Mediated Anaphylaxis and Desensitize Mast Cells to Subsequent Antigen Problem 

Siglec-Eight is an inhibitory receptor expressed on eosinophils and mast cells. On this examine, we took benefit of a novel Siglec-Eight transgenic mouse mannequin to evaluate the impression of modulating IgE-dependent mast cell degranulation and anaphylaxis utilizing a liposomal platform to show an allergen with or and not using a artificial glycan ligand for Siglec-8 (Sig8L). The speculation is that recruitment of Siglec-Eight to the IgE-FcεRI receptor complicated will inhibit allergen-induced mast cell degranulation. Codisplay of each allergen and Sig8L on liposomes profoundly suppresses IgE-mediated degranulation of mouse bone marrow-derived mast cells or rat basophilic leukemia cells expressing Siglec-8. In distinction, liposomes displaying solely Sig8L don’t have any vital suppression of antigenic liposome-induced degranulation, demonstrating that the inhibitory exercise by Siglec-Eight happens solely when Ag and Sig8L are on the identical particle.

In mouse fashions of anaphylaxis, show of Sig8L on antigenic liposomes fully suppresses IgE-mediated anaphylaxis in transgenic mice with mast cells expressing Siglec-Eight however has no safety in mice that don’t categorical Siglec-8. Moreover, mice shielded from anaphylaxis stay desensitized to subsequent allergen problem due to lack of Ag-specific IgE from the cell floor and accelerated clearance of IgE from the blood. Thus, though expression of human Siglec-Eight on murine mast cells doesn’t by itself modulate IgE-FcεRI-mediated cell activation, the enforced recruitment of Siglec-Eight to the FcεRI receptor by Sig8L-decorated antigenic liposomes ends in inhibition of degranulation and desensitization to subsequent Ag publicity.

The Traf2 DNx BCL2-tg Mouse Mannequin of Power Lymphocytic Leukemia/Small Lymphocytic Lymphoma Recapitulates the Biased IGHV Gene Utilization, Stereotypy, and Antigen-Particular HCDR3 Collection of Its Human Counterpart 

Power lymphocytic leukemia (CLL)/Small lymphocytic lymphoma (SLL) is a heterogeneous illness consisting of at the very least two separate subtypes, primarily based on the mutation standing of the immunoglobulin heavy chain variable gene (IGHV) sequence. Publicity to antigens appears to play a job in malignant transformation and within the choice and growth of extra aggressive CLL clones. Moreover, a biased utilization of explicit IGHV gene subgroups and the existence of stereotyped B-cell receptors (BCRs) are distinctive traits of human CLL. We have now beforehand described that Traf2DN/BCL2 double-transgenic (tg, +/+) mice develop CLL/SLL with excessive incidence with getting old. On this mannequin, TNF-Receptor Related Issue (TRAF)-2 deficiency cooperates with B cell lymphoma (BCL)-2 in selling CLL/SLL in mice by particularly implementing marginal zone (MZ) B cell differentiation and rendering B cells impartial of BAFF for survival. On this report, we have now carried out the sequencing of the IGHV-D-J rearrangements of B cell clones from the Traf2DN/BCL2-tg+/+ mice with CLL/SLL. The outcomes point out that these mice develop oligoclonal and monoclonal B cell expansions.

Allotransplantation of the oligoclonal populations into immunodeficient mice resulted within the preferential growth of one of many parental clones. The evaluation of the IGHV sequences indicated that 15% had been mutated (M) and 85% unmutated (UM). Moreover, whereas the Traf2DN/BCL2-tg-/- (wild-type), -/+ (BCL2 single-tg) and +/- (Traf2DNDN single-tg) littermates confirmed the expression of assorted IGHV gene subgroups, the CLL/SLL expanded clones from the Traf2DN/BCL2-tg+/+ (double-transgenic) mice confirmed a extra restricted IGHV gene subgroup utilization and an overrepresentation of explicit IGHV genes. As well as, the HCDR3-encoded protein sequence signifies the existence of stereotyped immunoglobulin (Ig) within the BCRs and powerful similarities with BCR recognizing autoantigens and pathogen-associated antigens. Altogether, these outcomes spotlight the exceptional similarities between the CLL/SLL developed by the Traf2DN/BCL2-tg+/+ mice and its human counterpart.

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

anti-FAS antigen

519-A-01mg 0,1 mg
EUR 267.5
  • Category: Antibody, Signal Transduction Antibodies, mAb
Description: anti-FAS antigen

anti-FAS antigen

519-A-1000ug 1000 ug
EUR 1282.5
  • Category: Antibody, Signal Transduction Antibodies, mAb
Description: anti-FAS antigen

anti-CD300 antigen

YF-PA17583 50 ul
EUR 363
Description: Mouse polyclonal to CD300 antigen

anti-CD300 antigen

YF-PA17584 50 ug
EUR 363
Description: Mouse polyclonal to CD300 antigen

anti-CD300 antigen

YF-PA17585 50 ul
EUR 363
Description: Mouse polyclonal to CD300 antigen

Mouse Anti-EBV Nuclear Antigen Monoclonal Antibody

DMAB3332-05mg 0.5 mg
EUR 969

Mouse Anti-EBV Nuclear Antigen Monoclonal Antibody

DMAB3332-1mg 1 mg
EUR 1469

Mouse Anti Melanoma associated antigen ELISA kit

E03M0220-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Mouse Anti Melanoma associated antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Anti Melanoma associated antigen ELISA kit

E03M0220-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Mouse Anti Melanoma associated antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Anti Melanoma associated antigen ELISA kit

E03M0220-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Mouse Anti Melanoma associated antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Anti soluble liver antigen ELISA kit

E03S0263-192T 192 tests
EUR 1270
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Mouse Anti soluble liver antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Anti soluble liver antigen ELISA kit

E03S0263-48 1 plate of 48 wells
EUR 520
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Mouse Anti soluble liver antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Anti soluble liver antigen ELISA kit

E03S0263-96 1 plate of 96 wells
EUR 685
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
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Description: A competitive ELISA for quantitative measurement of Mouse Anti soluble liver antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Anti-Ku80 Antigen Purified

11-496-C025 0.025 mg
EUR 108

Anti-Ku80 Antigen Purified

11-496-C100 0.1 mg
EUR 177

Anti-Carcinoembryonic Antigen antibody

STJ16100878 1 mL
EUR 668

Anti-Nucleolar Antigen antibody

STJ16101002 100 µg
EUR 354

Anti-Liver Antigen antibody

STJ16101073 100 µg
EUR 354

Anti-Liver Antigen antibody

STJ16101074 100 µg
EUR 354

Anti-Carcinoembryonic Antigen antibody

STJ96963 200 µl
EUR 197
Description: Carcinoembryonic antigen is a protein encoded by the CEACAM5 gene which is approximately 76,7 kDa. Carcinoembryonic antigen is localised to the cell membrane. It is involved in the metabolism of proteins and hematopoietic stem cell differentiation pathways and lineage-specific markers. It is a cell surface glycoprotein that plays a role in cell adhesion and in intracellular signalling. It may also regulate differentiation, apoptosis, and cell polarity and is used as a clinical biomarker for gastrointestinal cancers. Carcinoembryonic antigen is expressed in the intestine, liver, saliva, stomach and lung. Mutations in the CEACAM5 gene may be involved in urachal cancer. STJ96963 was developed from clone 10E1 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous Carcinoembryonic antigen proteins.

anti-Prostate Specific Antigen

YF-PA10281 50 ug
EUR 363
Description: Mouse polyclonal to Prostate Specific Antigen

anti-Prostate Specific Antigen

YF-PA10282 100 ug
EUR 403
Description: Rabbit polyclonal to Prostate Specific Antigen

Mouse Anti-Bacillus anthracis Protective Antigen Monoclonal Antibody

DMAB3024 1 mg
EUR 903

Mouse Anti-Bacillus anthracis Protective Antigen Monoclonal Antibody

DMAB3028 1 mg
EUR 955

Mouse Anti-Bacillus anthracis Protective Antigen Monoclonal Antibody

DMAB3029 1 mg
EUR 955

Mouse Anti-Bacillus anthracis Protective Antigen Monoclonal Antibody

DMAB3031 1 mg
EUR 903

Mouse Anti-Bacillus anthracis Spore Antigen Monoclonal Antibody

DMAB3033-05mg 0.5 mg
EUR 969

Mouse Anti-Bacillus anthracis Spore Antigen Monoclonal Antibody

DMAB3033-1mg 1 mg
EUR 1469

Mouse Anti-Bacillus anthracis Spore Antigen Monoclonal Antibody

DMAB3034-05mg 0.5 mg
EUR 969

Mouse Anti-Bacillus anthracis Spore Antigen Monoclonal Antibody

DMAB3034-1mg 1 mg
EUR 1469

Mouse Anti-Hepatitis B Core Antigen Monoclonal Antibody

DMAB3498 1 mg
EUR 833

Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody

DMAB3525 1 mg
EUR 781

Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody

DMAB3531 1 mg
EUR 741

Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody

DMAB3532 1 mg
EUR 741

Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody

DMAB3536-05mg 0.5 mg
EUR 969

Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody

DMAB3536-1mg 1 mg
EUR 1469

Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody

DMAB3537-05mg 0.5 mg
EUR 969

Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody

DMAB3537-1mg 1 mg
EUR 1469

Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody

DMAB3540 1 mg
EUR 741

Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody

DMAB3543 1 mg
EUR 741

Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody

DMAB3545 1 mg
EUR 632

Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody

DMAB3546 1 mg
EUR 632

Mouse Anti Borrelia Burgdorferi Flagellar Antigen Monoclonal Antibody

DMABT-51105MB 0.2 mg
EUR 715

Mouse Anti Chlamydia Trachomatis 30Kda Antigen Monoclonal Antibody

DMABT-51152MC 0.2 mg
EUR 663

Mouse Anti Hepatitis A Surface Antigen Monoclonal Antibody

DMABT-51310MH 0.2 mg
EUR 741

Mouse Anti Hepatitis B Core Antigen Monoclonal Antibody

DMABT-51311MH 0.2 mg
EUR 767

Mouse Anti Hepatitis B Core Antigen Monoclonal Antibody

DMABT-51312MH 0.2 mg
EUR 710

Mouse Anti Hepatitis B Core Antigen Monoclonal Antibody

DMABT-51314MH 0.2 mg
EUR 580

Mouse Anti Hepatitis B Core Antigen Monoclonal Antibody

DMABT-51315MH 0.2 mg
EUR 710

Mouse Anti Hepatitis B Core Antigen Monoclonal Antibody

DMABT-51316MH 0.2 mg
EUR 663

Mouse Anti Hepatitis B Core Antigen Monoclonal Antibody

DMABT-51317MH 0.2 mg
EUR 710

Mouse Anti Hepatitis B E Antigen Monoclonal Antibody

DMABT-51319MH 0.2 mg
EUR 767

Mouse Anti Hepatitis B Surface Antigen Monoclonal Antibody

DMABT-51323MH 0.2 mg
EUR 580

Mouse Anti Hepatitis B Surface Antigen Monoclonal Antibody

DMABT-51324MH 0.1 ml
EUR 445

Mouse Anti Hepatitis B Surface Antigen Monoclonal Antibody

DMABT-51325MH 1 ml
EUR 819

Mouse Anti Hepatitis B Surface Antigen Monoclonal Antibody

DMABT-51326MH 1 ml
EUR 445

Mouse Anti Hepatitis B Surface Antigen Monoclonal Antibody

DMABT-51327MH 6 ml
EUR 715

Mouse Anti Hepatitis B Surface Antigen Monoclonal Antibody

DMABT-51328MH 0.1 mg
EUR 741

Mouse Anti Hepatitis B X Antigen Monoclonal Antibody

DMABT-51330MH 0.25 mg
EUR 725

Mouse Anti Hepatitis C Core Antigen Monoclonal Antibody

DMABT-51332MH 0.1 mg
EUR 767

Mouse Anti Hepatitis C E1 Antigen Monoclonal Antibody

DMABT-51333MH 0.1 mg
EUR 944

Mouse Anti Hepatitis C E2 Antigen Monoclonal Antibody

DMABT-51334MH 0.1 mg
EUR 944

Mouse Anti Influenza A H5 Antigen Monoclonal Antibody

DMABT-51386MI 0.2 mg
EUR 663

Mouse Anti Influenza A H5 Antigen Monoclonal Antibody

DMABT-51388MI 0.2 mg
EUR 741

Mouse Anti Mycobacterium Tuberculosis 16Kda Antigen Monoclonal Antibody

DMABT-51441MM 0.1 mg
EUR 892

Mouse Anti Mycobacterium Tuberculosis 16Kda Antigen Monoclonal Antibody

DMABT-51442MM 0.1 mg
EUR 892

Mouse Anti Mycobacterium Tuberculosis 38Kda Antigen Monoclonal Antibody

DMABT-51444MM 0.2 mg
EUR 767

Mouse Anti Mycobacterium Tuberculosis 38Kda Antigen Monoclonal Antibody

DMABT-51446MM 0.2 mg
EUR 767

Mouse Anti Mycobacterium Tuberculosis 38Kda Antigen Monoclonal Antibody

DMABT-51448MM 0.2 mg
EUR 767

Mouse Anti Yersinia Pestis V Antigen Monoclonal Antibody

DMABT-51632MY 0.2 mg
EUR 767

Mouse Anti Yersinia Pestis V Antigen Monoclonal Antibody

DMABT-51634MY 0.2 mg
EUR 767

Mouse anti- extractable nuclear antigen antibody ELISA Kit

ELA-E1124m 96 Tests
EUR 865

Rat Anti Mouse F4/80 Antigen Monoclonal Antibody

CABT-47632RM 0.1 mg
EUR 663

Anti-Flavivirus group antigen Antibody

A1146-200
EUR 697

Anti-Flavivirus group antigen Antibody

A1147-200
EUR 697

anti-RhoD human antigen IgG1

131-A-01mg 0,1 mg
EUR 267.5
  • Category: Antibody, Blood Group Antibodies, mAb
Description: anti-RhoD human antigen IgG1

anti-RhoD human antigen IgG1

131-A-1000ug 1000 ug
EUR 1282.5
  • Category: Antibody, Blood Group Antibodies, mAb
Description: anti-RhoD human antigen IgG1

anti-Carcinoembryonic Antigen/CEA (10E1)

LF-MA20354 100 ug
EUR 354
Description: Mouse monoclonal to Carcinoembryonic Antigen (CEA)

Anti-HLA-DR antigen antibody

STJ16100045 1 mL
EUR 478

Anti-CD95/FAS antigen antibody

STJ16100141 100 µg
EUR 354

Anti-Rat CD4-antigen antibody

STJ16100150 1 mL
EUR 604

Anti-Myeloid Specific Antigen antibody

STJ16100158 100 µg
EUR 389

Anti-Myeloid Specific Antigen antibody

STJ16100170 100 µg
EUR 389

Anti-Myeloid Specific Antigen antibody

STJ16100171 100 µg
EUR 389

Anti-Myeloid Specific Antigen antibody

STJ16100172 100 µg
EUR 389

Anti-Hepatocyte Specific Antigen antibody

STJ16100376 1 mL
EUR 795

Anti-Melamona-Associated Antigen antibody

STJ16100389 1 mL
EUR 871

Anti-Melamona-Associated Antigen antibody

STJ16100390 1 mL
EUR 838

Anti-Melanoma Discr. Antigen antibody

STJ16100730 1 mL
EUR 290

Anti-Melanoma Discr. Antigen antibody

STJ16100731 1 mL
EUR 290

Anti-Melanoma Associated Antigen antibody

STJ16100732 1 mL
EUR 253

Anti-Melanoma Associated Antigen antibody

STJ16100733 1 mL
EUR 271

Anti-Melanoma Associated Antigen antibody

STJ16100734 1 mL
EUR 271

Anti-Melanoma Associated Antigen antibody

STJ16100735 1 mL
EUR 271

Anti-Ovarium Carcinoma Antigen antibody

STJ16100873 1 mL
EUR 290

Anti-Leukocyte Common Antigen antibody

STJ16100941 1 mL
EUR 481
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