Validation of the Effectiveness of Neutrophil

Validation of the Effectiveness of Neutrophil-to-lymphocyte Ratio (NLR) as a Predictive Consider Sufferers Present process Prostate Biopsy With Prostate Particular Antigen (PSA) Between 4.zero and 10.zero ng/ml

Background/goal: This examine aimed to entry the effectiveness of serum neutrophil-to-lymphocyte ratio (NLR) in sufferers present process prostate needle biopsy with a prostate particular antigen (PSA) between 4.zero and 10.zero ng/ml.

Sufferers and strategies: A complete of 633 circumstances had been eligible. We evaluated a number of components together with age, PSA, PSA-density (PSAD), platelet-to-lymphocyte ratio (PLR) and NLR within the presence or absence of prostate most cancers (PCa), retrospectively. We evaluated statistically the associations between every issue and pathological findings or Gleason rating.

Outcomes: A complete of 201 had been evaluated on this examine. Relating to the presence or absence of prostate most cancers, there have been statistically vital variations in age, PSA ranges, PSAD, the PLR and NLR. The imply NLR worth of the sufferers with PCa was considerably decrease in comparison with your entire cohort. Multivariate evaluation confirmed that age, PSAD, and NLR had been impartial danger components predicting PCa.

Conclusion: For sufferers having a PSA between 4.zero and 10.zero ng/ml, NLR was a predicting issue of PCa previous to prostate needle biopsy and an efficient biomarker and useful gizmo for avoiding pointless biopsies.

jointsjournal
jointsjournal

Anti-PAX6 (Stem Cell Marker) Monoclonal Antibody

M00273-1 100ug/vial
EUR 476.4
Description: Mouse Monoclonal PAX6 (Stem Cell Marker) Antibody. Validated in WB and tested in Chicken, Human, Mouse, Rat.

Stem Cell Set I

A9905-1 1 Set
EUR 184.8

Mouse Prostate stem cell antigen (Psca)

1-CSB-YP018840MO
  • EUR 604.80
  • EUR 318.00
  • EUR 2198.40
  • EUR 915.60
  • EUR 1459.20
  • EUR 400.80
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse Prostate stem cell antigen(Psca) expressed in Yeast

DiscoveryProbe? Stem Cell Compound Library

L1040-.1 100 uL/well(10 mM solution)
EUR 5223.6

Stem Cell MicroRNA Profiling Panel

RA620A-1 10 profiles
EUR 1406.4

Mouse Stem Cell Factor (SCF) AssayMax ELISA Kit

EMS1001-1 96 Well Plate
EUR 475.2

Mouse Nanog Stem Cell Differentiation Reporter (pGreenZeo, plasmid)

SR10031PA-1 10 ug
EUR 2098.8

SARS-CoV-2 Spike S1 RBD Protein, Mouse Fc-fusion

E80026
  • EUR 588.50
  • EUR 823.90
  • 20 ul
  • 50 ul

Mouse Nanog Stem Cell Differentiation Reporter (pGreenZeo, pre-packaged)

SR10031VA-1 >2 x 10^6 IFUs
EUR 906

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 336

Histone H3 Methylation Antibody Panel Pack I – Active Genes

C10000
  • EUR 928.26
  • EUR 588.50
  • 4 x 25 µg
  • 4 x 25 ul

Histone H3 Methylation Antibody Panel Pack I – Repression Genes

C10001
  • EUR 928.26
  • EUR 588.50
  • 4 x 25 µg
  • 4 x 25 ul

Histone H3 Methylation Antibody Panel Pack II – Active Genes

C10002
  • EUR 754.26
  • EUR 470.80
  • 3 x 25 µg
  • 3 x 25 ul

Histone H3 Methylation Antibody Panel Pack II – Repression Genes

C10003
  • EUR 928.26
  • EUR 588.50
  • 4 x 25 µg
  • 4 x 25 ul

Histone H3 Methylation Antibody Panel Pack III – Active Genes

C10004
  • EUR 928.26
  • EUR 588.50
  • 4 x 25 µg
  • 4 x 25 ul

Histone H3K4 Methylation Antibody Panel Pack

C10005
  • EUR 754.26
  • EUR 470.80
  • 3 x 25 µg
  • 3 x 25 ul

Histone H3K9 Methylation Antibody Panel Pack

C10006
  • EUR 754.26
  • EUR 470.80
  • 3 x 25 µg
  • 3 x 25 ul

Histone H3K27 Methylation Antibody Panel Pack

C10007
  • EUR 754.26
  • EUR 470.80
  • 3 x 25 µg
  • 3 x 25 ul

Histone H3K36 Methylation Antibody Panel Pack

C10008
  • EUR 754.26
  • EUR 470.80
  • 3 x 25 µg
  • 3 x 25 ul

Histone H3K79 Methylation Antibody Panel Pack

C10009
  • EUR 754.26
  • EUR 470.80
  • 3 x 25 µg
  • 3 x 25 ul

Histone H3 Acetylation Antibody Panel Pack I

C10010
  • EUR 928.26
  • EUR 588.50
  • 4 x 25 µg
  • 4 x 25 ul

Histone H3 Acetylation Antibody Panel Pack II

C10011
  • EUR 928.26
  • EUR 588.50
  • 4 x 25 µg
  • 4 x 25 ul

Histone H4K20 Methylation Antibody Panel Pack

C10012
  • EUR 754.26
  • EUR 470.80
  • 3 x 25 µg
  • 3 x 25 ul

Histone H4 Acetylation Antibody Panel Pack

C10013
  • EUR 754.26
  • EUR 470.80
  • 4 x 25 µg
  • 4 x 25 ul

Histone H3 Phosphorylation Antibody Panel Pack

C10014
  • EUR 754.26
  • EUR 470.80
  • 3 x 25 µg
  • 3 x 25 ul

Histone H3R2 Methylation Antibody Panel Pack

C10015
  • EUR 754.26
  • EUR 470.80
  • 3 x 25 µg
  • 3 x 25 ul

Histone H3R8 Methylation Antibody Panel Pack

C10016
  • EUR 754.26
  • EUR 470.80
  • 3 x 25 µg
  • 3 x 25 ul

Histone H3R17 Methylation Antibody Panel Pack

C10017
  • EUR 754.26
  • EUR 470.80
  • 3 x 25 µg
  • 3 x 25 ul

Histone H3R26 Methylation Antibody Panel Pack

C10018
  • EUR 754.26
  • EUR 470.80
  • 3 x 25 µg
  • 3 x 25 ul

Histone H4R3 Methylation Antibody Panel Pack

C10019
  • EUR 754.26
  • EUR 470.80
  • 3 x 25 µg
  • 3 x 25 ul

DNA Methylation Antibody Panel Pack I

C20000
  • EUR 458.46
  • EUR 270.60
  • 2 x 25 ul

DNMT3A Protein

E11000
  • EUR 971.76
  • EUR 618.20
  • 10 µg
  • 10 ul

TET1 Protein (Active)

E12002
  • EUR 387.12
  • EUR 225.50
  • 10 µg
  • 10 ul

DNMT3B Protein 

E14000
  • EUR 971.76
  • EUR 618.20
  • 10 µg
  • 10 ul

DNMT1 Protein 

E15000
  • EUR 971.76
  • EUR 618.20
  • 10 µg
  • 10 ul

HDAC1 Protein 

E24002
  • EUR 968.28
  • EUR 616.00
  • 50 µg
  • 50 ul

HDAC10 Protein 

E24003
  • EUR 968.28
  • EUR 616.00
  • 50 µg
  • 50 ul

HDAC11 Protein 

E24004
  • EUR 968.28
  • EUR 616.00
  • 50 µg
  • 50 ul

HDAC2 Protein 

E24005
  • EUR 968.28
  • EUR 616.00
  • 50 µg
  • 50 ul

HDAC3 Protein 

E24006
  • EUR 968.28
  • EUR 616.00
  • 50 µg
  • 50 ul

HDAC4 Protein 

E24007
  • EUR 968.28
  • EUR 616.00
  • 10 µg
  • 10 ul

HDAC5 Protein 

E24008
  • EUR 968.28
  • EUR 616.00
  • 10 µg
  • 10 ul

HDAC6 Protein 

E24009
  • EUR 968.28
  • EUR 616.00
  • 50 µg
  • 50 ul

HDAC7 Protein 

E24010
  • EUR 968.28
  • EUR 616.00
  • 10 µg
  • 10 ul

HDAC8 Protein 

E24011
  • EUR 968.28
  • EUR 616.00
  • 50 µg
  • 50 ul

HDAC9 Protein 

E24012
  • EUR 968.28
  • EUR 616.00
  • 10 µg
  • 10 ul

H3F3A Protein 

E35003
  • EUR 174.84
  • EUR 78.10
  • 50 µg
  • 50 ul

H4 Protein 

E35005
  • EUR 174.84
  • EUR 78.10
  • 50 µg
  • 50 ul

SOD1 Protein 

E70000
  • EUR 599.40
  • EUR 365.20
  • 25 µg
  • 25 ul

EpiMag HT (96-Well) Magnetic Separator

Q10002
  • EUR 416.70
  • EUR 258.50
  • 1/Pack
  • 1/Pack

EpiMag 96-Well Microplate (5/pack) 

Q10003
  • EUR 136.56
  • EUR 52.80
  • 5/pack
  • 5/pack

Human Genomic DNA 

X11000
  • Ask for price
  • EUR 235.40
  • 0.2 ml
  • 0.2 ml

Human Brain Genomic DNA  

X11001
  • Ask for price
  • EUR 77.00
  • 10 µg
  • 10 ul

SCA-1 Antibody

47996-100ul 100ul
EUR 399.6

SCA-1 Antibody

47996-50ul 50ul
EUR 286.8

SCF Stem Cell Factor Human Recombinant Protein

PROTP21583-1 Regular: 10ug
EUR 380.4
Description: Stem Cell Factor Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 165 amino acids and having a molecular mass of 18409 Dalton. ;The SCF is purified by proprietary chromatographic techniques.

StemBoost? Neural Stem Cell Reprogramming Cocktail (100X)

S238-1
EUR 222

Human Prostate stem cell antigen (PSCA)

1-CSB-YP018840HU
  • EUR 516.00
  • EUR 280.80
  • EUR 1809.60
  • EUR 770.40
  • EUR 1210.80
  • EUR 349.20
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Prostate stem cell antigen(PSCA) expressed in Yeast

Human Prostate stem cell antigen (PSCA)

1-CSB-EP018840HU
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Prostate stem cell antigen(PSCA) expressed in E.coli

Human Prostate stem cell antigen (PSCA)

1-CSB-EP018840HUa0
  • EUR 456.00
  • EUR 256.80
  • EUR 1570.80
  • EUR 672.00
  • EUR 1047.60
  • EUR 314.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Prostate stem cell antigen(PSCA) expressed in E.coli

Human Stem Cell Factor (SCF) AssayMax ELISA Kit

ES1001-1 96 Well Plate
EUR 475.2

ACE2, His-Tag Protein

E80019
  • EUR 612.70
  • EUR 1437.70
  • 20 ul
  • 100 ul

SARS-CoV-2 Spike S1 (13-665) Protein, Fc Fusion, Avi-tag

E80020
  • EUR 635.80
  • EUR 4276.80
  • 100 ul
  • 1 ml

SARS-CoV-2 Spike S1 (16-685) Protein, Avi-His-tag

E80021
  • EUR 635.80
  • EUR 4276.80
  • 100 ul
  • 1 ml

SARS-CoV-2 Spike S1 (16-685) Protein, Fc Fusion, Avi-tag

E80022
  • EUR 635.80
  • EUR 4276.80
  • 100 ul
  • 1 ml

SARS-CoV-2 Spike S1 RBD (V367F) Protein, Avi-His-tag

E80023
  • EUR 635.80
  • EUR 3934.70
  • 100 ul
  • 1 ml

SARS-CoV-2 Spike S1 RBD Protein, Avi-His-tag

E80024
  • EUR 635.80
  • EUR 4995.10
  • 100 ul
  • 1 ml

SARS-CoV-2 Spike S1 RBD Protein, Human Fc-Fusion, Avi-Tag

E80025
  • EUR 635.80
  • EUR 3934.70
  • 100 ul
  • 1 ml

SARS-CoV-2 Nucleocapsid Protein, Avi-His-tag

E80027
  • EUR 635.80
  • EUR 4087.60
  • 1 ml
  • 100 ul

Recombinant SARS-CoV-2 Spike Glycoprotein(S) (D614G), Partial

E80028
  • EUR 388.30
  • EUR 860.20
  • 20 ul
  • 100 ul

SCA-1 Conjugated Antibody

C47996 100ul
EUR 476.4

Anti-Periphilin 1 Antibody

A06996-1 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for Periphilin 1 Antibody (PPHLN1) detection.tested for WB in Human, Mouse.

Anti-Lyl-1 Antibody

A07491-1 100ul
EUR 476.4
Description: Rabbit Polyclonal Lyl-1 Antibody. Validated in IHC and tested in Human, Mouse, Rat.

Anti-GLI-1 Antibody

A07972-1 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for GLI-1 Antibody (ACSS1) detection. Tested with WB in Human, Mouse, Rat.

Anti-Cerebellin 1 Antibody

A09176-1 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for Cerebellin 1 Antibody (CBLN1) detection. Tested with WB in Human, Mouse, Rat.

Anti-DOC-1 Antibody

A09467-1 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for DOC-1 Antibody (CDK2AP1) detection. Tested with WB in Human, Mouse.

Anti-NPDC-1 Antibody

A12846-1 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for NPDC-1 Antibody (NPDC1) detection. Tested with WB in Human, Mouse, Rat.

Anti-ROBO-1 Antibody

A01530-1 100ug
EUR 546
Description: Rabbit Polyclonal ROBO-1 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-Bag-1 Antibody

A02423-1 50 ul
EUR 476.4
Description: Rabbit Polyclonal Bag-1 Antibody. Validated in IP, IHC and tested in Bovine, Canine, Human, Mouse, Rat.

Anti-TUB 1 Antibody

A02917-1 100ug/vial
EUR 352.8

Anti-Dok-1 Antibody

A03039-1 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for Dok-1 Antibody (DOK1) detection.tested for WB in Human, Mouse, Rat.

Anti-TFIIIB90-1 Antibody

A03761-1 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for TFIIIB90-1 Antibody (BRF1) detection.tested for WB in Human, Mouse.

Anti-Atrophin-1 Antibody

A03828-1 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for Atrophin-1 Antibody (ATN1) detection. Tested with WB in Human, Mouse, Rat.

Anti-CNG-1 Antibody

A05494-1 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for CNG-1 Antibody (CNGA1) detection. Tested with WB in Human, Mouse, Rat.

Anti-PAI-1 Antibody

A00637-1 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for PAI-1 Antibody (SERPINE1) detection.tested for WB in Human, Mouse, Rat.

Anti-Flk-1 Antibody

A00901-1 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for Flk-1 Antibody (KDR) detection.tested for WB in Human, Mouse.

Anti-EDG-1 Antibody

A01502-1 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for EDG-1 Antibody (S1PR1) detection.tested for WB in Human, Mouse, Rat.

Anti-PARP-1 Antibody

A00122-1 100ul
EUR 476.4
Description: Rabbit Polyclonal PARP-1 Antibody. Validated in ELISA, IP, IF, WB and tested in Human, Mouse.

Anti-Presenilin 1 Antibody

A00138-1 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for Presenilin 1 Antibody (PSEN1) detection. Tested with WB, IHC in Human, Mouse, Rat.

Methylamp 96 DNA Modification Kit 

P-1008
  • EUR 416.70
  • EUR 253.00
  • 96 Samples
  • 96 Samples

Nucleic Acid Isolation Enhancer (Glycogen Solution) 

R-1001
  • EUR 164.40
  • EUR 75.90
  • 500 µl
  • 500 ul

Methylamp PCR Enhancer 

R-1002
  • EUR 185.28
  • EUR 90.20
  • 400 Reactions
  • 400 Reactions

Streptavidin: HRP Conjugate

R-1098
  • EUR 218.34
  • EUR 107.80
  • 0.5 ml
  • 0.5 ml

Streptavidin 

R-1100
  • EUR 237.48
  • EUR 121.00
  • 1 mg
  • 1 ml

Protease Inhibitor Cocktail 

R-1101
  • EUR 176.58
  • EUR 79.20
  • 1 ml
  • 1 ml

Streptavidin-Coated Strip Microwell Plate (Flat) 

R-1102
  • EUR 361.02
  • EUR 204.60
  • 5/pk
  • 5/pk

DNA High Binding Solution

R-1103
  • EUR 267.06
  • EUR 140.80
  • 30 ml
  • 30 ml

DTT Solution 

R-1104
  • EUR 131.34
  • EUR 48.40
  • 1 ml, 500 mM
  • 1 ml, 500 mM

EpiQuik Nuclear Extraction Kit 

OP-0002
  • EUR 350.58
  • EUR 211.20
  • 100 Assays
  • 100 Extractions

Human Prostate stem cell antigen(PSCA) ELISA kit

1-CSB-EL018840HU
  • EUR 964.80
  • EUR 6118.80
  • EUR 3244.80
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Prostate stem cell antigen(PSCA) in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

[Preparation of a novel tri-specific T cell engager targeting CD19 antigen and its anti-leukemia effect exploration] 

Goal: To arrange a novel tri-specific T cell engager (19TriTE) concentrating on CD19 antigen, and to analyze its immunotherapeutic impact on CD19-positive hematological malignancies.

Strategies: 19TriTE was constructed by molecular cloning know-how and efficiently expressed via the eukaryotic expressing system. The results of 19TriTE on the proliferation and activation of T cells, in addition to the particular cytotoxicity in opposition to CD19 constructive tumor cell strains had been verified.

Outcomes: ①19TriTE expressing plasmid was constructed and efficiently expressed via the eukaryotic expressing system. ②19TriTE can particularly bind to T cells and Nalm6 cells, with equilibrium dissociation constants of 19.21 nmol/L and 11.67 nmol/L, respectively. ③The expression charges of CD69 constructive T cells and CD25 constructive T cells had been 35.4% and 49.8% respectively, when 2 nmol/L 19TriTE had been added within the co-culture system, which had been considerably greater than these within the management group. ④19TriTE can considerably promote the proliferation of T cells.

Absolutely the depend of T cells expanded from the preliminary a million to 74 million with an 74 fold enhance on the focus of 1 nmol/L on day 12. ⑤19TriTE can considerably mediate T cells killing of CD19 constructive goal cells in a dose-dependent method. On the focus of 10 nmol/L, the goal cells lysis reached 50%. ⑥Degranulation experiment verified that 19TriTE can activate T cells within the presence of CD19 constructive goal cells, and the activation of T cells positively correlated with the dose of 19TriTE. ⑦When 19TriTE fusion protein co-cultured with T cells and goal cells overexpression RFP and luciferase genes respectively, 19TriTE can notably mediate T cells killing of CD19 constructive goal cells via fluorescent microscope or bioluminescence imaging know-how.

Conclusion: On this examine, we efficiently constructed and expressed 19TriTE fusion protein and verified that it could possibly successfully activate T cells and promote their proliferation in vitro. On the similar time, it could possibly bind to CD19 constructive goal cells and T cells, in addition to improve T cells anti-leukemia impact in vitro, offering the inspiration for additional scientific analysis.

Nanoparticles Displaying Allergen and Siglec-Eight Ligands Suppress IgE-FcεRI-Mediated Anaphylaxis and Desensitize Mast Cells to Subsequent Antigen Problem 

Siglec-Eight is an inhibitory receptor expressed on eosinophils and mast cells. On this examine, we took benefit of a novel Siglec-Eight transgenic mouse mannequin to evaluate the impression of modulating IgE-dependent mast cell degranulation and anaphylaxis utilizing a liposomal platform to show an allergen with or and not using a artificial glycan ligand for Siglec-8 (Sig8L). The speculation is that recruitment of Siglec-Eight to the IgE-FcεRI receptor complicated will inhibit allergen-induced mast cell degranulation. Codisplay of each allergen and Sig8L on liposomes profoundly suppresses IgE-mediated degranulation of mouse bone marrow-derived mast cells or rat basophilic leukemia cells expressing Siglec-8. In distinction, liposomes displaying solely Sig8L don’t have any vital suppression of antigenic liposome-induced degranulation, demonstrating that the inhibitory exercise by Siglec-Eight happens solely when Ag and Sig8L are on the identical particle.

In mouse fashions of anaphylaxis, show of Sig8L on antigenic liposomes fully suppresses IgE-mediated anaphylaxis in transgenic mice with mast cells expressing Siglec-Eight however has no safety in mice that don’t categorical Siglec-8. Moreover, mice shielded from anaphylaxis stay desensitized to subsequent allergen problem due to lack of Ag-specific IgE from the cell floor and accelerated clearance of IgE from the blood. Thus, though expression of human Siglec-Eight on murine mast cells doesn’t by itself modulate IgE-FcεRI-mediated cell activation, the enforced recruitment of Siglec-Eight to the FcεRI receptor by Sig8L-decorated antigenic liposomes ends in inhibition of degranulation and desensitization to subsequent Ag publicity.

The Traf2 DNx BCL2-tg Mouse Mannequin of Power Lymphocytic Leukemia/Small Lymphocytic Lymphoma Recapitulates the Biased IGHV Gene Utilization, Stereotypy, and Antigen-Particular HCDR3 Collection of Its Human Counterpart 

Power lymphocytic leukemia (CLL)/Small lymphocytic lymphoma (SLL) is a heterogeneous illness consisting of at the very least two separate subtypes, primarily based on the mutation standing of the immunoglobulin heavy chain variable gene (IGHV) sequence. Publicity to antigens appears to play a job in malignant transformation and within the choice and growth of extra aggressive CLL clones. Moreover, a biased utilization of explicit IGHV gene subgroups and the existence of stereotyped B-cell receptors (BCRs) are distinctive traits of human CLL. We have now beforehand described that Traf2DN/BCL2 double-transgenic (tg, +/+) mice develop CLL/SLL with excessive incidence with getting old. On this mannequin, TNF-Receptor Related Issue (TRAF)-2 deficiency cooperates with B cell lymphoma (BCL)-2 in selling CLL/SLL in mice by particularly implementing marginal zone (MZ) B cell differentiation and rendering B cells impartial of BAFF for survival. On this report, we have now carried out the sequencing of the IGHV-D-J rearrangements of B cell clones from the Traf2DN/BCL2-tg+/+ mice with CLL/SLL. The outcomes point out that these mice develop oligoclonal and monoclonal B cell expansions.

Allotransplantation of the oligoclonal populations into immunodeficient mice resulted within the preferential growth of one of many parental clones. The evaluation of the IGHV sequences indicated that 15% had been mutated (M) and 85% unmutated (UM). Moreover, whereas the Traf2DN/BCL2-tg-/- (wild-type), -/+ (BCL2 single-tg) and +/- (Traf2DNDN single-tg) littermates confirmed the expression of assorted IGHV gene subgroups, the CLL/SLL expanded clones from the Traf2DN/BCL2-tg+/+ (double-transgenic) mice confirmed a extra restricted IGHV gene subgroup utilization and an overrepresentation of explicit IGHV genes. As well as, the HCDR3-encoded protein sequence signifies the existence of stereotyped immunoglobulin (Ig) within the BCRs and powerful similarities with BCR recognizing autoantigens and pathogen-associated antigens. Altogether, these outcomes spotlight the exceptional similarities between the CLL/SLL developed by the Traf2DN/BCL2-tg+/+ mice and its human counterpart.

anti-CD300 antigen

YF-PA17583 50 ul
EUR 435.6
Description: Mouse polyclonal to CD300 antigen

anti-CD300 antigen

YF-PA17584 50 ug
EUR 435.6
Description: Mouse polyclonal to CD300 antigen

anti-CD300 antigen

YF-PA17585 50 ul
EUR 435.6
Description: Mouse polyclonal to CD300 antigen

Mouse Anti-EBV Nuclear Antigen Monoclonal Antibody

DMAB3332-05mg 0.5 mg
EUR 1162.8

Mouse Anti-EBV Nuclear Antigen Monoclonal Antibody

DMAB3332-1mg 1 mg
EUR 1762.8

Mouse Anti Melanoma associated antigen ELISA kit

E03M0220-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Anti Melanoma associated antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Anti Melanoma associated antigen ELISA kit

E03M0220-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Anti Melanoma associated antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Anti Melanoma associated antigen ELISA kit

E03M0220-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Anti Melanoma associated antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Anti soluble liver antigen ELISA kit

E03S0263-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Anti soluble liver antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Anti soluble liver antigen ELISA kit

E03S0263-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Anti soluble liver antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Anti soluble liver antigen ELISA kit

E03S0263-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Anti soluble liver antigen in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Anti-Ku80 Antigen Purified

11-496-C025 0.025 mg
EUR 129.6

Anti-Ku80 Antigen Purified

11-496-C100 0.1 mg
EUR 212.4

Anti-Carcinoembryonic Antigen antibody

STJ96963 200 µl
EUR 236.4
Description: Carcinoembryonic antigen is a protein encoded by the CEACAM5 gene which is approximately 76,7 kDa. Carcinoembryonic antigen is localised to the cell membrane. It is involved in the metabolism of proteins and hematopoietic stem cell differentiation pathways and lineage-specific markers. It is a cell surface glycoprotein that plays a role in cell adhesion and in intracellular signalling. It may also regulate differentiation, apoptosis, and cell polarity and is used as a clinical biomarker for gastrointestinal cancers. Carcinoembryonic antigen is expressed in the intestine, liver, saliva, stomach and lung. Mutations in the CEACAM5 gene may be involved in urachal cancer. STJ96963 was developed from clone 10E1 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous Carcinoembryonic antigen proteins.

Anti-Carcinoembryonic Antigen antibody

STJ16100878 1 mL
EUR 801.6

Anti-Nucleolar Antigen antibody

STJ16101002 100 µg
EUR 424.8

Anti-Liver Antigen antibody

STJ16101073 100 µg
EUR 424.8

Anti-Liver Antigen antibody

STJ16101074 100 µg
EUR 424.8

anti-Prostate Specific Antigen

YF-PA10281 50 ug
EUR 435.6
Description: Mouse polyclonal to Prostate Specific Antigen

anti-Prostate Specific Antigen

YF-PA10282 100 ug
EUR 483.6
Description: Rabbit polyclonal to Prostate Specific Antigen

Mouse IgG Antigen

IM122 1 ml
EUR 342
Description: Mouse IgG Antigen by Cygnus Technologies is available in Europe via Gentaur.

Rat Anti Mouse F4/80 Antigen Monoclonal Antibody

CABT-47632RM 0.1 mg
EUR 795.6

Mouse Anti-Bacillus anthracis Protective Antigen Monoclonal Antibody

DMAB3024 1 mg
EUR 1083.6

Mouse Anti-Bacillus anthracis Protective Antigen Monoclonal Antibody

DMAB3028 1 mg
EUR 1146

Mouse Anti-Bacillus anthracis Protective Antigen Monoclonal Antibody

DMAB3029 1 mg
EUR 1146

Mouse Anti-Bacillus anthracis Protective Antigen Monoclonal Antibody

DMAB3031 1 mg
EUR 1083.6

Mouse Anti-Bacillus anthracis Spore Antigen Monoclonal Antibody

DMAB3033-05mg 0.5 mg
EUR 1162.8

Mouse Anti-Bacillus anthracis Spore Antigen Monoclonal Antibody

DMAB3033-1mg 1 mg
EUR 1762.8

Mouse Anti-Bacillus anthracis Spore Antigen Monoclonal Antibody

DMAB3034-05mg 0.5 mg
EUR 1162.8

Mouse Anti-Bacillus anthracis Spore Antigen Monoclonal Antibody

DMAB3034-1mg 1 mg
EUR 1762.8

Mouse Anti-Hepatitis B Core Antigen Monoclonal Antibody

DMAB3498 1 mg
EUR 999.6

Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody

DMAB3525 1 mg
EUR 937.2

Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody

DMAB3531 1 mg
EUR 889.2

Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody

DMAB3532 1 mg
EUR 889.2

Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody

DMAB3536-05mg 0.5 mg
EUR 1162.8

Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody

DMAB3536-1mg 1 mg
EUR 1762.8

Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody

DMAB3537-05mg 0.5 mg
EUR 1162.8

Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody

DMAB3537-1mg 1 mg
EUR 1762.8

Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody

DMAB3540 1 mg
EUR 889.2

Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody

DMAB3543 1 mg
EUR 889.2

Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody

DMAB3545 1 mg
EUR 758.4

Mouse Anti-Hepatitis B Surface Antigen Monoclonal Antibody

DMAB3546 1 mg
EUR 758.4

Mouse Anti Borrelia Burgdorferi Flagellar Antigen Monoclonal Antibody

DMABT-51105MB 0.2 mg
EUR 858

Mouse Anti Chlamydia Trachomatis 30Kda Antigen Monoclonal Antibody

DMABT-51152MC 0.2 mg
EUR 795.6

Mouse Anti Hepatitis A Surface Antigen Monoclonal Antibody

DMABT-51310MH 0.2 mg
EUR 889.2

Mouse Anti Hepatitis B Core Antigen Monoclonal Antibody

DMABT-51311MH 0.2 mg
EUR 920.4

Mouse Anti Hepatitis B Core Antigen Monoclonal Antibody

DMABT-51312MH 0.2 mg
EUR 852

Mouse Anti Hepatitis B Core Antigen Monoclonal Antibody

DMABT-51314MH 0.2 mg
EUR 696

Mouse Anti Hepatitis B Core Antigen Monoclonal Antibody

DMABT-51315MH 0.2 mg
EUR 852

Mouse Anti Hepatitis B Core Antigen Monoclonal Antibody

DMABT-51316MH 0.2 mg
EUR 795.6

Mouse Anti Hepatitis B Core Antigen Monoclonal Antibody

DMABT-51317MH 0.2 mg
EUR 852

Mouse Anti Hepatitis B E Antigen Monoclonal Antibody

DMABT-51319MH 0.2 mg
EUR 920.4

Mouse Anti Hepatitis B Surface Antigen Monoclonal Antibody

DMABT-51323MH 0.2 mg
EUR 696

Mouse Anti Hepatitis B Surface Antigen Monoclonal Antibody

DMABT-51324MH 0.1 ml
EUR 534

Mouse Anti Hepatitis B Surface Antigen Monoclonal Antibody

DMABT-51325MH 1 ml
EUR 982.8

Mouse Anti Hepatitis B Surface Antigen Monoclonal Antibody

DMABT-51326MH 1 ml
EUR 534

Mouse Anti Hepatitis B Surface Antigen Monoclonal Antibody

DMABT-51327MH 6 ml
EUR 858

Mouse Anti Hepatitis B Surface Antigen Monoclonal Antibody

DMABT-51328MH 0.1 mg
EUR 889.2

Mouse Anti Hepatitis B X Antigen Monoclonal Antibody

DMABT-51330MH 0.25 mg
EUR 870

Mouse Anti Hepatitis C Core Antigen Monoclonal Antibody

DMABT-51332MH 0.1 mg
EUR 920.4

Mouse Anti Hepatitis C E1 Antigen Monoclonal Antibody

DMABT-51333MH 0.1 mg
EUR 1132.8

Mouse Anti Hepatitis C E2 Antigen Monoclonal Antibody

DMABT-51334MH 0.1 mg
EUR 1132.8

Mouse Anti Influenza A H5 Antigen Monoclonal Antibody

DMABT-51386MI 0.2 mg
EUR 795.6

Mouse Anti Influenza A H5 Antigen Monoclonal Antibody

DMABT-51388MI 0.2 mg
EUR 889.2

Mouse Anti Mycobacterium Tuberculosis 16Kda Antigen Monoclonal Antibody

DMABT-51441MM 0.1 mg
EUR 1070.4

Mouse Anti Mycobacterium Tuberculosis 16Kda Antigen Monoclonal Antibody

DMABT-51442MM 0.1 mg
EUR 1070.4

Mouse Anti Mycobacterium Tuberculosis 38Kda Antigen Monoclonal Antibody

DMABT-51444MM 0.2 mg
EUR 920.4

Mouse Anti Mycobacterium Tuberculosis 38Kda Antigen Monoclonal Antibody

DMABT-51446MM 0.2 mg
EUR 920.4

Mouse Anti Mycobacterium Tuberculosis 38Kda Antigen Monoclonal Antibody

DMABT-51448MM 0.2 mg
EUR 920.4

Mouse Anti Yersinia Pestis V Antigen Monoclonal Antibody

DMABT-51632MY 0.2 mg
EUR 920.4

Mouse Anti Yersinia Pestis V Antigen Monoclonal Antibody

DMABT-51634MY 0.2 mg
EUR 920.4

Mouse anti- extractable nuclear antigen antibody ELISA Kit

ELA-E1124m 96 Tests
EUR 1038

anti-RhoD human antigen IgG1

131-A-01mg 0,1 mg
EUR 321
Description: anti-RhoD human antigen IgG1

anti-RhoD human antigen IgG1

131-A-1000ug 1000 ug
EUR 1539
Description: anti-RhoD human antigen IgG1

Anti-Flavivirus group antigen Antibody

A1146-200
EUR 836.4

Anti-Flavivirus group antigen Antibody

A1147-200
EUR 836.4

anti-Carcinoembryonic Antigen/CEA (10E1)

LF-MA20354 100 ug
EUR 424.8
Description: Mouse monoclonal to Carcinoembryonic Antigen (CEA)

Anti-Anthrax Protective Antigen antibody

STJ99283 200 µl
EUR 236.4
Description: Mouse monoclonal to Anthrax Protective Antigen.

Anti-HLA-DR antigen antibody

STJ16100045 1 mL
EUR 573.6

Anti-CD95/FAS antigen antibody

STJ16100141 100 µg
EUR 424.8

Anti-Rat CD4-antigen antibody

STJ16100150 1 mL
EUR 724.8

Anti-Myeloid Specific Antigen antibody

STJ16100158 100 µg
EUR 466.8

Anti-Myeloid Specific Antigen antibody

STJ16100170 100 µg
EUR 466.8

Anti-Myeloid Specific Antigen antibody

STJ16100171 100 µg
EUR 466.8

Anti-Myeloid Specific Antigen antibody

STJ16100172 100 µg
EUR 466.8

Anti-Hepatocyte Specific Antigen antibody

STJ16100376 1 mL
EUR 954

Anti-Melamona-Associated Antigen antibody

STJ16100389 1 mL
EUR 1045.2

Anti-Melamona-Associated Antigen antibody

STJ16100390 1 mL
EUR 1005.6

Anti-Melanoma Discr. Antigen antibody

STJ16100730 1 mL
EUR 348

Anti-Melanoma Discr. Antigen antibody

STJ16100731 1 mL
EUR 348

Anti-Melanoma Associated Antigen antibody

STJ16100732 1 mL
EUR 303.6

Anti-Melanoma Associated Antigen antibody

STJ16100733 1 mL
EUR 325.2

Anti-Melanoma Associated Antigen antibody

STJ16100734 1 mL
EUR 325.2

Anti-Melanoma Associated Antigen antibody

STJ16100735 1 mL
EUR 325.2

Anti-Ovarium Carcinoma Antigen antibody

STJ16100873 1 mL
EUR 348

Anti-Leukocyte Common Antigen antibody

STJ16100941 1 mL
EUR 577.2

Anti-Prostate Specific Antigen antibody

STJ16100961 1 mL
EUR 577.2

Anti-Myeloid Specific Antigen antibody

STJ16100989 100 µg
EUR 424.8

anti-Blood Group Kell Antigen

YF-PA12828 50 ul
EUR 435.6
Description: Mouse polyclonal to Blood Group Kell Antigen

anti-NY-REN-50 antigen

YF-PA19832 50 ul
EUR 435.6
Description: Mouse polyclonal to NY-REN-50 antigen

Anti-Prostate Specific Antigen (1B1)

YF-MA11962 100 ug
EUR 435.6
Description: Mouse monoclonal to Prostate Specific Antigen

Mouse Monoclonal Anti-human carcinoembryonic antigen (CEA) (clone 1)

CEA11-M 500 ug
EUR 578.4

Mouse Monoclonal Anti-human carcinoembryonic antigen (CEA) (clone 2)

CEA12-M 500 ug
EUR 578.4

Rat Anti Mouse F4/80 Antigen Monoclonal Antibody,APC

CABT-47617RM 100 TEST
EUR 920.4

Rat Anti Mouse F4/80 Antigen Monoclonal Antibody,Biotin

CABT-47620RM 0.1 mg
EUR 889.2

Rat Anti Mouse F4/80 Antigen Monoclonal Antibody,FITC

CABT-47625RM 0.1 mg
EUR 889.2

Mouse Anti Epstein-Barr Virus Nuclear Antigen Monoclonal Antibody

DMABT-51237ME 0.1 mg
EUR 982.8

Mouse Anti Epstein-Barr Virus Nuclear Antigen Monoclonal Antibody

DMABT-51238ME 0.1 mg
EUR 858

Mouse Anti Hepatitis B Core Antigen Monoclonal Antibody,HRP

DMABT-51313MH 0.1 mg
EUR 920.4

Mouse Anti Hepatitis C Ns-3 Antigen Monoclonal Antibody

DMABT-51336MH 0.2 mg
EUR 920.4

Mouse Anti Hepatitis C Ns-3 Antigen Monoclonal Antibody

DMABT-51337MH 0.2 mg
EUR 920.4

Mouse Anti Hepatitis C Ns-3 Antigen Monoclonal Antibody

DMABT-51338MH 0.2 mg
EUR 920.4

Mouse Anti Hepatitis C Ns-3 Antigen Monoclonal Antibody

DMABT-51339MH 0.1 mg
EUR 1132.8

Mouse Anti Hepatitis C Ns-3 Antigen Monoclonal Antibody

DMABT-51340MH 0.1 mg
EUR 1132.8

Mouse Anti Hepatitis C Ns-3 Antigen Monoclonal Antibody

DMABT-51341MH 0.1 mg
EUR 1513.2

Mouse Anti Hepatitis C Ns-4A Antigen Monoclonal Antibody

DMABT-51344MH 0.1 mg
EUR 1132.8

Mouse Anti Hepatitis C Ns-5 Antigen Monoclonal Antibody

DMABT-51346MH 0.2 mg
EUR 920.4

Mouse Anti Hepatitis C Ns-5 Antigen Monoclonal Antibody

DMABT-51348MH 0.2 mg
EUR 920.4

Mouse Anti Hepatitis C Ns-5A Antigen Monoclonal Antibody

DMABT-51351MH 0.1 mg
EUR 1513.2

Mouse Anti paraneoplastic Ma antigen 2 antibody ELISA kit

E03A0480-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Anti paraneoplastic Ma antigen 2 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Anti paraneoplastic Ma antigen 2 antibody ELISA kit

E03A0480-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Anti paraneoplastic Ma antigen 2 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Anti paraneoplastic Ma antigen 2 antibody ELISA kit

E03A0480-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Anti paraneoplastic Ma antigen 2 antibody in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Monoclonal Anti-Hepatitis Surface Antigen (HBsAg)-HRP Conjugate

HBA12-HRP 1 ml
EUR 416.4

Mouse Monoclonal Anti-Hepatitis Surface Antigen (HBsAg) (clone 1)

HBA12-M 1 mg
EUR 343.2

Mouse Monoclonal Anti-Hepatitis Surface Antigen (HBsAg) (clone 2)

HBA13-M 1 mg
EUR 343.2

Mouse CD63 antigen (Cd63)

1-CSB-EP004950MOe0
  • EUR 606.00
  • EUR 318.00
  • EUR 2192.40
  • EUR 919.20
  • EUR 1461.60
  • EUR 402.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse CD63 antigen(Cd63) ,partial expressed in E.coli

Mouse CD81 antigen (Cd81)

1-CSB-EP004960MO
  • EUR 606.00
  • EUR 318.00
  • EUR 2192.40
  • EUR 919.20
  • EUR 1461.60
  • EUR 402.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse CD81 antigen(Cd81),partial expressed in E.coli

Mouse CD82 antigen (Cd82)

1-CSB-EP004961MO
  • EUR 606.00
  • EUR 318.00
  • EUR 2192.40
  • EUR 919.20
  • EUR 1461.60
  • EUR 402.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse CD82 antigen(Cd82) ,partial expressed in E.coli

anti-B human blood antigen IgM

134-A-01mg 0,1 mg
EUR 321
Description: anti-B human blood antigen IgM

anti-B human blood antigen IgM

134-A-1000ug 1000 ug
EUR 1539
Description: anti-B human blood antigen IgM

anti-AB human blood antigen IgM

135-A-01mg 0,1 mg
EUR 321
Description: anti-AB human blood antigen IgM

anti-AB human blood antigen IgM

135-A-1000ug 1000 ug
EUR 1539
Description: anti-AB human blood antigen IgM

anti-M human blood antigen IgM

144-A-01mg 0,1 mg
EUR 321
Description: anti-M human blood antigen IgM

anti-M human blood antigen IgM

144-A-1000ug 1000 ug
EUR 1539
Description: anti-M human blood antigen IgM

Blood Antigen ig2b: Anti-N Human

145-A-01mg 0,1 mg
EUR 321
Description: anti-N human blood antigen Ig2b

Blood Antigen ig2b: Anti-N Human

145-A-1000ug 1000 ug
EUR 1539
Description: anti-N human blood antigen Ig2b

Anti-Retinal S antigen/SAG Antibody

A03775 100ug/vial
EUR 352.8

Anti-Melanoma-associated antigen D1 Antibody

A05037 100ul
EUR 476.4
Description: Rabbit Polyclonal Melanoma-associated antigen D1 Antibody. Validated in WB and tested in Human, Mouse, Rat.

Anti-Carcinoembryonic Antigen Antibody (C66/1260)

A1464-100
EUR 574.8

Anti-Carcinoembryonic Antigen, pan Antibody (Cocktail)

A1465-100
EUR 574.8

anti-Rabies G antigen monoclonal antibody

010-A-01mg 0,1 mg
EUR 321
Description: anti-Rabies G antigen monoclonal antibody. Produced against a recombinant protein.

anti-Rabies G antigen monoclonal antibody

010-A-1000ug 1000 ug
EUR 1539
Description: anti-Rabies G antigen monoclonal antibody. Produced against a recombinant protein.

Anti-HBcAG Hepatitis B Core Antigen

030-A-01mg 0,1 mg
EUR 321
Description: anti-HBcAg core IgM (monoclonal) Produced against recombinant HBcAg core antigen.

Anti-HBcAG Hepatitis B Core Antigen

030-A-1000ug 1000 ug
EUR 1539
Description: anti-HBcAg core IgM (monoclonal) Produced against recombinant HBcAg core antigen.

anti-HBsAg surface antigen IgG1 mAb

032-A-01mg 0,1 mg
EUR 321
Description: anti-HBsAg surface antigen IgG1 (monoclonal) Produced against HBsAg purified from human sera pool.

anti-HBsAg surface antigen IgG1 mAb

032-A-1000ug 1000 ug
EUR 1539
Description: anti-HBsAg surface antigen IgG1 (monoclonal) Produced against HBsAg purified from human sera pool.

Anti-TF Antigen Peptide P30-1

H-5988.0001 1.0mg
EUR 283.2
Description: Sum Formula: C94H130N26O19; CAS# [573664-50-3] net

Anti-TF Antigen Peptide P30-1

H-5988.0005 5.0mg
EUR 1023.6
Description: Sum Formula: C94H130N26O19; CAS# [573664-50-3] net

Anti-Prostate Specific Antigen/KLK3 Antibody

PB9259 100ug/vial
EUR 352.8

Anti-Proximal Nephrogenic Renal Antigen antibody

STJ16100515 100 µg
EUR 424.8
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