Validation of the Effectiveness of Neutrophil

Validation of the Effectiveness of Neutrophil-to-lymphocyte Ratio (NLR) as a Predictive Consider Sufferers Present process Prostate Biopsy With Prostate Particular Antigen (PSA) Between 4.zero and 10.zero ng/ml

Background/goal: This examine aimed to entry the effectiveness of serum neutrophil-to-lymphocyte ratio (NLR) in sufferers present process prostate needle biopsy with a prostate particular antigen (PSA) between 4.zero and 10.zero ng/ml.

Sufferers and strategies: A complete of 633 circumstances had been eligible. We evaluated a number of components together with age, PSA, PSA-density (PSAD), platelet-to-lymphocyte ratio (PLR) and NLR within the presence or absence of prostate most cancers (PCa), retrospectively. We evaluated statistically the associations between every issue and pathological findings or Gleason rating.

Outcomes: A complete of 201 had been evaluated on this examine. Relating to the presence or absence of prostate most cancers, there have been statistically vital variations in age, PSA ranges, PSAD, the PLR and NLR. The imply NLR worth of the sufferers with PCa was considerably decrease in comparison with your entire cohort. Multivariate evaluation confirmed that age, PSAD, and NLR had been impartial danger components predicting PCa.

Conclusion: For sufferers having a PSA between 4.zero and 10.zero ng/ml, NLR was a predicting issue of PCa previous to prostate needle biopsy and an efficient biomarker and useful gizmo for avoiding pointless biopsies.

jointsjournal
jointsjournal

Recombinant mouse Prostate stem cell antigen

MBS9422457-05mg 0.5mg
EUR 1655

Recombinant mouse Prostate stem cell antigen

MBS9422457-5x05mg 5x0.5mg
EUR 7290

Mouse Prostate Stem Cell Antigen ELISA Kit

MBS057229-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse Prostate Stem Cell Antigen ELISA Kit

MBS057229-48StripWells 48-Strip-Wells
EUR 550

Mouse Prostate Stem Cell Antigen ELISA Kit

MBS057229-5x96StripWells 5x96-Strip-Wells
EUR 3420

Mouse Prostate Stem Cell Antigen ELISA Kit

MBS057229-96StripWells 96-Strip-Wells
EUR 765

Mouse Prostate stem cell antigen ELISA Kit

MBS289860-10x96StripWells 10x96-Strip-Wells
EUR 4630

Mouse Prostate stem cell antigen ELISA Kit

MBS289860-48StripWells 48-Strip-Wells
EUR 440

Mouse Prostate stem cell antigen ELISA Kit

MBS289860-5x96StripWells 5x96-Strip-Wells
EUR 2480

Mouse Prostate stem cell antigen ELISA Kit

MBS289860-96StripWells 96-Strip-Wells
EUR 580

StemTAG Stem Cell Colony Formation Assay (Cell Recovery Compatible)

CBA-325 96 assays
EUR 1027.2
Description: Our StemTAG 96-Well Stem Cell Colony Formation Assay provides a high-throughput method to quantify ES cells in just 7-10 days, and no manual cell counting is required. Once colonies are formed, they may be analyzed in three different ways: 1. Lyse cells, then quantify in a fluorescence plate reader using dye included in the kit; 2. Lyse cells, then quantify alkaline phosphatase activity using reagents provided; or 3. Recover colonies from matrix for further culture or analysis.

StemTAG Stem Cell Colony Formation Assay (Cell Recovery Compatible)

CBA-325-5 5 x 96 assays
EUR 4033.2
Description: Our StemTAG 96-Well Stem Cell Colony Formation Assay provides a high-throughput method to quantify ES cells in just 7-10 days, and no manual cell counting is required. Once colonies are formed, they may be analyzed in three different ways: 1. Lyse cells, then quantify in a fluorescence plate reader using dye included in the kit; 2. Lyse cells, then quantify alkaline phosphatase activity using reagents provided; or 3. Recover colonies from matrix for further culture or analysis.

Recombinant Mouse Prostate stem cell antigen (Psca)

CSB-YP018840MO 5939 mg Ask for price

Recombinant Mouse Prostate stem cell antigen(Psca)

AP72740 each Ask for price

Recombinant Mouse Prostate stem cell antigen (Psca)

RPC20241-100ug 100ug
EUR 569.8

Recombinant Mouse Prostate stem cell antigen (Psca)

RPC20241-20ug 20ug
EUR 353.4

Recombinant Mouse Prostate stem cell antigen (Psca)

MBS962351-002mgYeast 0.02mg(Yeast)
EUR 320

Recombinant Mouse Prostate stem cell antigen (Psca)

MBS962351-01mgYeast 0.1mg(Yeast)
EUR 515

Recombinant Mouse Prostate stem cell antigen (Psca)

MBS962351-05mgYeast 0.5mg(Yeast)
EUR 1260

Recombinant Mouse Prostate stem cell antigen (Psca)

MBS962351-5x05mgYeast 5x0.5mg(Yeast)
EUR 5485

HESCA-1 (Human Embryonic Stem Cell Antigen-1)

MBS604449-01mg 0.1mg
EUR 785

HESCA-1 (Human Embryonic Stem Cell Antigen-1)

MBS604449-5x01mg 5x0.1mg
EUR 3385

Mouse Prostate stem cell antigen (PSCA) ELISA Kit

abx520719-96tests 96 tests
EUR 886.8

Mouse Psca/ Prostate stem cell antigen ELISA Kit

E1215Mo 1 Kit
EUR 543

Mouse Prostate stem cell antigen, Psca ELISA KIT

ELI-22375m 96tests
EUR 736

Mouse Prostate stem cell antigen (PSCA) ELISA Kit

RK13577 96T
EUR 280

Mouse Psca / Prostate stem cell antigen ELISA Kit

E8693m 96T
EUR 776

LY6E/Stem cell antigen 1 Polyclonal Antibody

MBS9236660-01mL 0.1mL
EUR 415

LY6E/Stem cell antigen 1 Polyclonal Antibody

MBS9236660-5x01mL 5x0.1mL
EUR 1841

StemTAG PCR Primer Set for Stem Cell Characterization

CBA-303 1 kit
EUR 470.4
Description: StemTAG PCR Primer Set for Stem Cell Characterization includes 7 primer pairs: Oct-4, NANOG, AFP, Flk-1, and NCAM, plus GAPDH and beta-actin as controls.

Total Protein - Murine Embryonic Stem Cell Line D3

CBA-305 500 ?g
EUR 414
Description:
  • Isolated from mouse ES-D3 cell line
  • Presented as 500 µg at 1 mg/mL in NP-40 Solubilization Buffer

LY6E (Lymphocyte Antigen 6E, Ly-6E, Retinoic Acid-induced Gene E Protein, RIG-E, Stem Cell Antigen 2, SCA-2, Thymic Shared Antigen 1, TSA-1, 9804, RIGE, SCA2, TSA1)

MBS630318-01mg 0.1mg
EUR 665

LY6E (Lymphocyte Antigen 6E, Ly-6E, Retinoic Acid-induced Gene E Protein, RIG-E, Stem Cell Antigen 2, SCA-2, Thymic Shared Antigen 1, TSA-1, 9804, RIGE, SCA2, TSA1)

MBS630318-5x01mg 5x0.1mg
EUR 2850

Prostate stem cell antigen

AP86675 1mg
EUR 2640

Prostate stem cell antigen

AP87071 1mg
EUR 2640

LY6E (Lymphocyte Antigen 6E, Ly-6E, Retinoic Acid-induced Gene E Protein, RIG-E, Stem Cell Antigen 2, SCA-2, Thymic Shared Antigen 1, TSA-1, 9804, RIGE, SCA2, TSA1) (AP)

MBS6485594-01mL 0.1mL
EUR 920

LY6E (Lymphocyte Antigen 6E, Ly-6E, Retinoic Acid-induced Gene E Protein, RIG-E, Stem Cell Antigen 2, SCA-2, Thymic Shared Antigen 1, TSA-1, 9804, RIGE, SCA2, TSA1) (AP)

MBS6485594-5x01mL 5x0.1mL
EUR 3990

LY6E (Lymphocyte Antigen 6E, Ly-6E, Retinoic Acid-induced Gene E Protein, RIG-E, Stem Cell Antigen 2, SCA-2, Thymic Shared Antigen 1, TSA-1, 9804, RIGE, SCA2, TSA1) APC

MBS6485595-01mL 0.1mL
EUR 920

LY6E (Lymphocyte Antigen 6E, Ly-6E, Retinoic Acid-induced Gene E Protein, RIG-E, Stem Cell Antigen 2, SCA-2, Thymic Shared Antigen 1, TSA-1, 9804, RIGE, SCA2, TSA1) APC

MBS6485595-5x01mL 5x0.1mL
EUR 3990

LY6E (Lymphocyte Antigen 6E, Ly-6E, Retinoic Acid-induced Gene E Protein, RIG-E, Stem Cell Antigen 2, SCA-2, Thymic Shared Antigen 1, TSA-1, 9804, RIGE, SCA2, TSA1) (FITC)

MBS6485597-01mL 0.1mL
EUR 920

LY6E (Lymphocyte Antigen 6E, Ly-6E, Retinoic Acid-induced Gene E Protein, RIG-E, Stem Cell Antigen 2, SCA-2, Thymic Shared Antigen 1, TSA-1, 9804, RIGE, SCA2, TSA1) (FITC)

MBS6485597-5x01mL 5x0.1mL
EUR 3990

LY6E (Lymphocyte Antigen 6E, Ly-6E, Retinoic Acid-induced Gene E Protein, RIG-E, Stem Cell Antigen 2, SCA-2, Thymic Shared Antigen 1, TSA-1, 9804, RIGE, SCA2, TSA1) (HRP)

MBS6485598-01mL 0.1mL
EUR 920

LY6E (Lymphocyte Antigen 6E, Ly-6E, Retinoic Acid-induced Gene E Protein, RIG-E, Stem Cell Antigen 2, SCA-2, Thymic Shared Antigen 1, TSA-1, 9804, RIGE, SCA2, TSA1) (HRP)

MBS6485598-5x01mL 5x0.1mL
EUR 3990

LY6E (Lymphocyte Antigen 6E, Ly-6E, Retinoic Acid-induced Gene E Protein, RIG-E, Stem Cell Antigen 2, SCA-2, Thymic Shared Antigen 1, TSA-1, 9804, RIGE, SCA2, TSA1) (PE)

MBS6485604-01mL 0.1mL
EUR 920

LY6E (Lymphocyte Antigen 6E, Ly-6E, Retinoic Acid-induced Gene E Protein, RIG-E, Stem Cell Antigen 2, SCA-2, Thymic Shared Antigen 1, TSA-1, 9804, RIGE, SCA2, TSA1) (PE)

MBS6485604-5x01mL 5x0.1mL
EUR 3990

OPCA01291-20UG - Recombinant Mouse Prostate stem cell antigen

OPCA01291-20UG 20ug
EUR 315

OPCA01291-100UG - Recombinant Mouse Prostate stem cell antigen

OPCA01291-100UG 100ug
EUR 462

OPCA01291-500UG - Recombinant Mouse Prostate stem cell antigen

OPCA01291-500UG 500ug
EUR 1276

Psca (untagged) - Mouse prostate stem cell antigen (Psca), (10ug)

MC211324 10 µg Ask for price

LY6E (Lymphocyte Antigen 6E, Ly-6E, Retinoic Acid-induced Gene E Protein, RIG-E, Stem Cell Antigen 2, SCA-2, Thymic Shared Antigen 1, TSA-1, 9804, RIGE, SCA2, TSA1) (Biotin)

MBS6485596-01mL 0.1mL
EUR 920

LY6E (Lymphocyte Antigen 6E, Ly-6E, Retinoic Acid-induced Gene E Protein, RIG-E, Stem Cell Antigen 2, SCA-2, Thymic Shared Antigen 1, TSA-1, 9804, RIGE, SCA2, TSA1) (Biotin)

MBS6485596-5x01mL 5x0.1mL
EUR 3990

CytoSelect Proliferating Cell Nuclear Antigen (PCNA) ELISA Kit

CBA-254 96 assays
EUR 672
Description: Cell Biolabs? CytoSelect Proliferating Cell Nuclear Antigen (PCNA) ELISA Kit is an enzyme immunoassay developed for the detection and quantitation of PCNA from nuclear and whole cell extracts.  The kit detects PCNA from mouse, rat and human, and has a detection sensitivity limit of 12.5 ng/mLPCNA.  Each kit provides sufficient reagents to perform up to 96 assays including standard curve and unknown samples. 

LY6E (Lymphocyte Antigen 6E, Ly-6E, Retinoic Acid-induced Gene E Protein, RIG-E, Stem Cell Antigen 2, SCA-2, Thymic Shared Antigen 1, TSA-1, 9804, RIGE, SCA2, TSA1) (MaxLight 405)

MBS6485599-01mL 0.1mL
EUR 920

LY6E (Lymphocyte Antigen 6E, Ly-6E, Retinoic Acid-induced Gene E Protein, RIG-E, Stem Cell Antigen 2, SCA-2, Thymic Shared Antigen 1, TSA-1, 9804, RIGE, SCA2, TSA1) (MaxLight 405)

MBS6485599-5x01mL 5x0.1mL
EUR 3990

LY6E (Lymphocyte Antigen 6E, Ly-6E, Retinoic Acid-induced Gene E Protein, RIG-E, Stem Cell Antigen 2, SCA-2, Thymic Shared Antigen 1, TSA-1, 9804, RIGE, SCA2, TSA1) (MaxLight 490)

MBS6485600-01mL 0.1mL
EUR 920

LY6E (Lymphocyte Antigen 6E, Ly-6E, Retinoic Acid-induced Gene E Protein, RIG-E, Stem Cell Antigen 2, SCA-2, Thymic Shared Antigen 1, TSA-1, 9804, RIGE, SCA2, TSA1) (MaxLight 490)

MBS6485600-5x01mL 5x0.1mL
EUR 3990

LY6E (Lymphocyte Antigen 6E, Ly-6E, Retinoic Acid-induced Gene E Protein, RIG-E, Stem Cell Antigen 2, SCA-2, Thymic Shared Antigen 1, TSA-1, 9804, RIGE, SCA2, TSA1) (MaxLight 550)

MBS6485601-01mL 0.1mL
EUR 920

LY6E (Lymphocyte Antigen 6E, Ly-6E, Retinoic Acid-induced Gene E Protein, RIG-E, Stem Cell Antigen 2, SCA-2, Thymic Shared Antigen 1, TSA-1, 9804, RIGE, SCA2, TSA1) (MaxLight 550)

MBS6485601-5x01mL 5x0.1mL
EUR 3990

LY6E (Lymphocyte Antigen 6E, Ly-6E, Retinoic Acid-induced Gene E Protein, RIG-E, Stem Cell Antigen 2, SCA-2, Thymic Shared Antigen 1, TSA-1, 9804, RIGE, SCA2, TSA1) (MaxLight 650)

MBS6485602-01mL 0.1mL
EUR 920

LY6E (Lymphocyte Antigen 6E, Ly-6E, Retinoic Acid-induced Gene E Protein, RIG-E, Stem Cell Antigen 2, SCA-2, Thymic Shared Antigen 1, TSA-1, 9804, RIGE, SCA2, TSA1) (MaxLight 650)

MBS6485602-5x01mL 5x0.1mL
EUR 3990

LY6E (Lymphocyte Antigen 6E, Ly-6E, Retinoic Acid-induced Gene E Protein, RIG-E, Stem Cell Antigen 2, SCA-2, Thymic Shared Antigen 1, TSA-1, 9804, RIGE, SCA2, TSA1) (MaxLight 750)

MBS6485603-01mL 0.1mL
EUR 920

LY6E (Lymphocyte Antigen 6E, Ly-6E, Retinoic Acid-induced Gene E Protein, RIG-E, Stem Cell Antigen 2, SCA-2, Thymic Shared Antigen 1, TSA-1, 9804, RIGE, SCA2, TSA1) (MaxLight 750)

MBS6485603-5x01mL 5x0.1mL
EUR 3990

Psca (GFP-tagged) - Mouse prostate stem cell antigen (Psca), (10ug)

MG215317 10 µg Ask for price

Psca (Myc-DDK-tagged) - Mouse prostate stem cell antigen (Psca)

MR215317 10 µg Ask for price

Prostate Stem Cell Antigen Antibody

8C0310 50ug
EUR 368
Description: Prostate Stem Cell Antigen Antibody

Prostate Stem Cell Antigen Antibody

33476 100ul
EUR 319

Prostate Stem Cell Antigen Antibody

33476-100ul 100ul
EUR 302.4

Prostate Stem Cell Antigen Antibody

33476-50ul 50ul
EUR 224.4

Prostate Stem Cell Antigen Antibody

E033476 100μg/100μl
EUR 255
Description: Available in various conjugation types.

Prostate Stem Cell Antigen Antibody

E11-0310C 100μg/100μl
EUR 225
Description: Available in various conjugation types.

Prostate Stem Cell Antigen Antibody

E19-8709-1 50ug/50ul
EUR 145
Description: Available in various conjugation types.

Prostate Stem Cell Antigen Antibody

E19-8709-2 100ug/100ul
EUR 225
Description: Available in various conjugation types.

Prostate Stem Cell Antigen Antibody

DF8709 200ul
EUR 420

Prostate Stem Cell Antigen Antibody

DF8709-100ul 100ul
EUR 280

Prostate Stem Cell Antigen Antibody

DF8709-200ul 200ul
EUR 350

Prostate Stem Cell Antigen Antibody

ABD8709 100ug
EUR 325

Prostate Stem Cell Antigen Antibody

MBS9400891-005mL 0.05mL
EUR 245

Prostate Stem Cell Antigen Antibody

MBS9400891-01mL 0.1mL
EUR 305

Prostate Stem Cell Antigen Antibody

MBS9400891-5x01mL 5x0.1mL
EUR 1230

Prostate Stem Cell Antigen Antibody

MBS8532743-005mg 0.05mg
EUR 235

Prostate Stem Cell Antigen Antibody

MBS8532743-01mg 0.1mg
EUR 305

Prostate Stem Cell Antigen Antibody

MBS8532743-01mLAF405M 0.1mL(AF405M)
EUR 465

Prostate Stem Cell Antigen Antibody

MBS8532743-01mLAF546 0.1mL(AF546)
EUR 465

Prostate Stem Cell Antigen Antibody

MBS8532743-01mLAF750 0.1mL(AF750)
EUR 465

Prostate Stem Cell Antigen Antibody

MBS853379-01mg 0.1mg
EUR 305

Prostate Stem Cell Antigen Antibody

MBS853379-01mLAF405L 0.1mL(AF405L)
EUR 465

Prostate Stem Cell Antigen Antibody

MBS853379-01mLAF405S 0.1mL(AF405S)
EUR 465

Prostate Stem Cell Antigen Antibody

MBS853379-01mLAF610 0.1mL(AF610)
EUR 465

Prostate Stem Cell Antigen Antibody

MBS853379-01mLAF635 0.1mL(AF635)
EUR 465

Prostate Stem Cell Antigen Antibody

MBS9609026-01mL 0.1mL
EUR 260

Prostate Stem Cell Antigen Antibody

MBS9609026-02mL 0.2mL
EUR 305

Prostate Stem Cell Antigen Antibody

MBS9609026-5x02mL 5x0.2mL
EUR 1220

Prostate Stem Cell Antigen Antibody

MBS9504710-005mL 0.05mL
EUR 285

Prostate Stem Cell Antigen Antibody

MBS9504710-01mL 0.1mL
EUR 385

Prostate Stem Cell Antigen Antibody

MBS9504710-5x01mL 5x0.1mL
EUR 1590

Prostate Stem Cell Antigen Antibody

MBS9510061-005mL 0.05mL
EUR 285

Prostate Stem Cell Antigen Antibody

MBS9510061-01mL 0.1mL
EUR 385

Prostate Stem Cell Antigen Antibody

MBS9510061-5x01mL 5x0.1mL
EUR 1590

Recombinant Mouse Prostate stem cell antigen Protein, His, Yeast-1mg

QP9353-ye-1mg 1mg
EUR 2763.6

Recombinant Mouse Prostate stem cell antigen Protein, His, Yeast-100ug

QP9353-ye-100ug 100ug
EUR 685.2

[Preparation of a novel tri-specific T cell engager targeting CD19 antigen and its anti-leukemia effect exploration] 

Goal: To arrange a novel tri-specific T cell engager (19TriTE) concentrating on CD19 antigen, and to analyze its immunotherapeutic impact on CD19-positive hematological malignancies.

Strategies: 19TriTE was constructed by molecular cloning know-how and efficiently expressed via the eukaryotic expressing system. The results of 19TriTE on the proliferation and activation of T cells, in addition to the particular cytotoxicity in opposition to CD19 constructive tumor cell strains had been verified.

Outcomes: ①19TriTE expressing plasmid was constructed and efficiently expressed via the eukaryotic expressing system. ②19TriTE can particularly bind to T cells and Nalm6 cells, with equilibrium dissociation constants of 19.21 nmol/L and 11.67 nmol/L, respectively. ③The expression charges of CD69 constructive T cells and CD25 constructive T cells had been 35.4% and 49.8% respectively, when 2 nmol/L 19TriTE had been added within the co-culture system, which had been considerably greater than these within the management group. ④19TriTE can considerably promote the proliferation of T cells.

Absolutely the depend of T cells expanded from the preliminary a million to 74 million with an 74 fold enhance on the focus of 1 nmol/L on day 12. ⑤19TriTE can considerably mediate T cells killing of CD19 constructive goal cells in a dose-dependent method. On the focus of 10 nmol/L, the goal cells lysis reached 50%. ⑥Degranulation experiment verified that 19TriTE can activate T cells within the presence of CD19 constructive goal cells, and the activation of T cells positively correlated with the dose of 19TriTE. ⑦When 19TriTE fusion protein co-cultured with T cells and goal cells overexpression RFP and luciferase genes respectively, 19TriTE can notably mediate T cells killing of CD19 constructive goal cells via fluorescent microscope or bioluminescence imaging know-how.

Conclusion: On this examine, we efficiently constructed and expressed 19TriTE fusion protein and verified that it could possibly successfully activate T cells and promote their proliferation in vitro. On the similar time, it could possibly bind to CD19 constructive goal cells and T cells, in addition to improve T cells anti-leukemia impact in vitro, offering the inspiration for additional scientific analysis.

Nanoparticles Displaying Allergen and Siglec-Eight Ligands Suppress IgE-FcεRI-Mediated Anaphylaxis and Desensitize Mast Cells to Subsequent Antigen Problem 

Siglec-Eight is an inhibitory receptor expressed on eosinophils and mast cells. On this examine, we took benefit of a novel Siglec-Eight transgenic mouse mannequin to evaluate the impression of modulating IgE-dependent mast cell degranulation and anaphylaxis utilizing a liposomal platform to show an allergen with or and not using a artificial glycan ligand for Siglec-8 (Sig8L). The speculation is that recruitment of Siglec-Eight to the IgE-FcεRI receptor complicated will inhibit allergen-induced mast cell degranulation. Codisplay of each allergen and Sig8L on liposomes profoundly suppresses IgE-mediated degranulation of mouse bone marrow-derived mast cells or rat basophilic leukemia cells expressing Siglec-8. In distinction, liposomes displaying solely Sig8L don’t have any vital suppression of antigenic liposome-induced degranulation, demonstrating that the inhibitory exercise by Siglec-Eight happens solely when Ag and Sig8L are on the identical particle.

In mouse fashions of anaphylaxis, show of Sig8L on antigenic liposomes fully suppresses IgE-mediated anaphylaxis in transgenic mice with mast cells expressing Siglec-Eight however has no safety in mice that don’t categorical Siglec-8. Moreover, mice shielded from anaphylaxis stay desensitized to subsequent allergen problem due to lack of Ag-specific IgE from the cell floor and accelerated clearance of IgE from the blood. Thus, though expression of human Siglec-Eight on murine mast cells doesn’t by itself modulate IgE-FcεRI-mediated cell activation, the enforced recruitment of Siglec-Eight to the FcεRI receptor by Sig8L-decorated antigenic liposomes ends in inhibition of degranulation and desensitization to subsequent Ag publicity.

The Traf2 DNx BCL2-tg Mouse Mannequin of Power Lymphocytic Leukemia/Small Lymphocytic Lymphoma Recapitulates the Biased IGHV Gene Utilization, Stereotypy, and Antigen-Particular HCDR3 Collection of Its Human Counterpart 

Power lymphocytic leukemia (CLL)/Small lymphocytic lymphoma (SLL) is a heterogeneous illness consisting of at the very least two separate subtypes, primarily based on the mutation standing of the immunoglobulin heavy chain variable gene (IGHV) sequence. Publicity to antigens appears to play a job in malignant transformation and within the choice and growth of extra aggressive CLL clones. Moreover, a biased utilization of explicit IGHV gene subgroups and the existence of stereotyped B-cell receptors (BCRs) are distinctive traits of human CLL. We have now beforehand described that Traf2DN/BCL2 double-transgenic (tg, +/+) mice develop CLL/SLL with excessive incidence with getting old. On this mannequin, TNF-Receptor Related Issue (TRAF)-2 deficiency cooperates with B cell lymphoma (BCL)-2 in selling CLL/SLL in mice by particularly implementing marginal zone (MZ) B cell differentiation and rendering B cells impartial of BAFF for survival. On this report, we have now carried out the sequencing of the IGHV-D-J rearrangements of B cell clones from the Traf2DN/BCL2-tg+/+ mice with CLL/SLL. The outcomes point out that these mice develop oligoclonal and monoclonal B cell expansions.

Allotransplantation of the oligoclonal populations into immunodeficient mice resulted within the preferential growth of one of many parental clones. The evaluation of the IGHV sequences indicated that 15% had been mutated (M) and 85% unmutated (UM). Moreover, whereas the Traf2DN/BCL2-tg-/- (wild-type), -/+ (BCL2 single-tg) and +/- (Traf2DNDN single-tg) littermates confirmed the expression of assorted IGHV gene subgroups, the CLL/SLL expanded clones from the Traf2DN/BCL2-tg+/+ (double-transgenic) mice confirmed a extra restricted IGHV gene subgroup utilization and an overrepresentation of explicit IGHV genes. As well as, the HCDR3-encoded protein sequence signifies the existence of stereotyped immunoglobulin (Ig) within the BCRs and powerful similarities with BCR recognizing autoantigens and pathogen-associated antigens. Altogether, these outcomes spotlight the exceptional similarities between the CLL/SLL developed by the Traf2DN/BCL2-tg+/+ mice and its human counterpart.

Anti-Murine Panendothelial Cell Antigen (MECA-32) Antibody

MBS4158532-5x01mg 5x0.1mg
EUR 3880

Mouse Anti-Hepatitis B Surface Antigen Antibody (1834)

MAB12230-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for Hepatitis B virus surface antigen (1834).

Mouse Anti-Hepatitis B Surface Antigen Antibody (1837)

MAB12231-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for Hepatitis B virus surface antigen (1837)

Mouse Anti-Hepatitis B Surface Antigen Antibody (1838)

MAB12232-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for Hepatitis B virus surface antigen (1838)

Mouse Anti-Hepatitis B Virus E Antigen Antibody (1892)

MAB12226-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for Hepatitis B virus e antigen (1892)

Mouse Anti-Hepatitis B Virus E Antigen Antibody (1893)

MAB12227-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for Hepatitis B virus e antigen (1893)

Mouse Anti-Hepatitis B Virus E Antigen Antibody (1894)

MAB12228-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for Hepatitis B virus e antigen (1894)

Mouse Anti-Hepatitis B Virus E Antigen Antibody (M132)

MAB12298-100 0.1
EUR 276.84
Description: Mouse monoclonal antibody specific for Hepatitis B virus e antigen (M132)

Mouse Anti-Hepatitis B Virus E Antigen Antibody (M132)

MAB12298-500 0.5
EUR 695.29
Description: Mouse monoclonal antibody specific for Hepatitis B virus e antigen (M132)

Mouse Anti-Hepatitis B Virus E Antigen Antibody (M133)

MAB12299-100 0.1
EUR 276.84
Description: Mouse monoclonal antibody specific for Hepatitis B virus e antigen (M133)

Mouse Anti-Hepatitis B Virus E Antigen Antibody (M133)

MAB12299-500 0.5
EUR 695.29
Description: Mouse monoclonal antibody specific for Hepatitis B virus e antigen (M133)

PLVAP (Plasmalemma Vesicle-Associated Protein, Plasmalemma Vesicle Protein 1, PV-1, MECA-32 Antigen, Pv1) (AP)

MBS6248246-01mL 0.1(mL
EUR 860

PLVAP (Plasmalemma Vesicle-Associated Protein, Plasmalemma Vesicle Protein 1, PV-1, MECA-32 Antigen, Pv1) (AP)

MBS6248246-5x01mL 5x0.1mL
EUR 3720

PLVAP (Plasmalemma Vesicle-Associated Protein, Plasmalemma Vesicle Protein 1, PV-1, MECA-32 Antigen, Pv1) (HRP)

MBS6251180-01mL 0.1(mL
EUR 860

PLVAP (Plasmalemma Vesicle-Associated Protein, Plasmalemma Vesicle Protein 1, PV-1, MECA-32 Antigen, Pv1) (HRP)

MBS6251180-5x01mL 5x0.1mL
EUR 3720

PLVAP (Plasmalemma Vesicle-Associated Protein, Plasmalemma Vesicle Protein 1, PV-1, MECA-32 Antigen, Pv1) (PE)

MBS6252121-01mL 0.1(mL
EUR 860

PLVAP (Plasmalemma Vesicle-Associated Protein, Plasmalemma Vesicle Protein 1, PV-1, MECA-32 Antigen, Pv1) (PE)

MBS6252121-5x01mL 5x0.1mL
EUR 3720

PLVAP (Plasmalemma Vesicle-Associated Protein, Plasmalemma Vesicle Protein 1, PV-1, MECA-32 Antigen, Pv1) (FITC)

MBS6250161-01mL 0.1(mL
EUR 860

PLVAP (Plasmalemma Vesicle-Associated Protein, Plasmalemma Vesicle Protein 1, PV-1, MECA-32 Antigen, Pv1) (FITC)

MBS6250161-5x01mL 5x0.1mL
EUR 3720

PLVAPC (Plasmalemma Vesicle-Associated Protein, Plasmalemma Vesicle Protein 1, PV-1, MECA-32 Antigen, Pv1) (APC)

MBS6269097-01mL 0.1mL
EUR 860

PLVAPC (Plasmalemma Vesicle-Associated Protein, Plasmalemma Vesicle Protein 1, PV-1, MECA-32 Antigen, Pv1) (APC)

MBS6269097-5x01mL 5x0.1mL
EUR 3720

PLVAP (Plasmalemma Vesicle-Associated Protein, Plasmalemma Vesicle Protein 1, PV-1, MECA-32 Antigen, Pv1) (MaxLight 490)

MBS6254194-01mL 0.1(mL
EUR 860

PLVAP (Plasmalemma Vesicle-Associated Protein, Plasmalemma Vesicle Protein 1, PV-1, MECA-32 Antigen, Pv1) (MaxLight 490)

MBS6254194-5x01mL 5x0.1mL
EUR 3720

PLVAP (Plasmalemma Vesicle-Associated Protein, Plasmalemma Vesicle Protein 1, PV-1, MECA-32 Antigen, Pv1) (MaxLight 550)

MBS6255234-01mL 0.1(mL
EUR 860

PLVAP (Plasmalemma Vesicle-Associated Protein, Plasmalemma Vesicle Protein 1, PV-1, MECA-32 Antigen, Pv1) (MaxLight 550)

MBS6255234-5x01mL 5x0.1mL
EUR 3720

PLVAP (Plasmalemma Vesicle-Associated Protein, Plasmalemma Vesicle Protein 1, PV-1, MECA-32 Antigen, Pv1) (MaxLight 405)

MBS6253154-01mL 0.1(mL
EUR 860

PLVAP (Plasmalemma Vesicle-Associated Protein, Plasmalemma Vesicle Protein 1, PV-1, MECA-32 Antigen, Pv1) (MaxLight 405)

MBS6253154-5x01mL 5x0.1mL
EUR 3720

PLVAP (Plasmalemma Vesicle-Associated Protein, Plasmalemma Vesicle Protein 1, PV-1, MECA-32 Antigen, Pv1) (MaxLight 750)

MBS6257313-01mL 0.1mL
EUR 860

PLVAP (Plasmalemma Vesicle-Associated Protein, Plasmalemma Vesicle Protein 1, PV-1, MECA-32 Antigen, Pv1) (MaxLight 750)

MBS6257313-5x01mL 5x0.1mL
EUR 3720

PLVAP (Plasmalemma Vesicle-Associated Protein, Plasmalemma Vesicle Protein 1, PV-1, MECA-32 Antigen, Pv1) (MaxLight 650)

MBS6256274-01mL 0.1(mL
EUR 860

PLVAP (Plasmalemma Vesicle-Associated Protein, Plasmalemma Vesicle Protein 1, PV-1, MECA-32 Antigen, Pv1) (MaxLight 650)

MBS6256274-5x01mL 5x0.1mL
EUR 3720

Rat Anti-Mouse MAdCAM-1 Monoclonal antibody, clone MECA-367

CABT-L4373-1mg 1 mg
EUR 1076.4

Rat Anti-Mouse MAdCAM-1 Monoclonal antibody, clone MECA-367

CABT-L4373-5mg 5 mg
EUR 2886

Rat Anti-Mouse MAdCAM-1 Monoclonal antibody, clone MECA-367

CABT-L4373 1 mg; 5 mg Ask for price
Description: Rat

Borrelia Afzelii Antigen

NAT41583-100 0.1
EUR 391.66
Description: Harvested bacteria are washed and detergent solubilized to produce a cytoplasmic extract enriched with lipoproteins and outer surface proteins (OSPs). The antigen is presented in phosphate buffered saline containing 1 % n-octyl-β-D-glucopyranoside.

Borrelia Afzelii Antigen

NAT41583-500 0.5
EUR 1176.24
Description: Harvested bacteria are washed and detergent solubilized to produce a cytoplasmic extract enriched with lipoproteins and outer surface proteins (OSPs). The antigen is presented in phosphate buffered saline containing 1 % n-octyl-β-D-glucopyranoside.

Borrelia Garinii Antigen

NAT41584-100 0.1
EUR 391.66
Description: Harvested bacteria are washed and detergent solubilized to produce a cytoplasmic extract enriched with lipoproteins and outer surface proteins (OSPs). The antigen is presented in phosphate buffered saline containing 1 % n-octyl-β-D-glucopyranoside.

Borrelia Garinii Antigen

NAT41584-500 0.5
EUR 1176.24
Description: Harvested bacteria are washed and detergent solubilized to produce a cytoplasmic extract enriched with lipoproteins and outer surface proteins (OSPs). The antigen is presented in phosphate buffered saline containing 1 % n-octyl-β-D-glucopyranoside.

Brucella Abortus Antigen

NAT41599-100 0.1
EUR 391.66
Description: Brucella abortus lysate, produced by fermentation.

Brucella Abortus Antigen

NAT41599-500 0.5
EUR 1176.24
Description: Brucella abortus lysate, produced by fermentation.

Candida Albicans Antigen

NAT41601-100 0.1
EUR 391.66
Description: Candida albicans is grown on solid medium, washed, disrupted and subjected to an extraction process. The antigen consists of cytoplasmic and cell wall components.

Candida Albicans Antigen

NAT41601-500 0.5
EUR 1176.24
Description: Candida albicans is grown on solid medium, washed, disrupted and subjected to an extraction process. The antigen consists of cytoplasmic and cell wall components.

Canine Parvovirus Antigen

NAT41594-100 0.1
EUR 391.66
Description: Canine Parvovirus, produced in CRFK cells.

Canine Coronavirus Antigen

NAT41590-100 0.1
EUR 391.66
Description: Canine Coronavirus produced in A-72 cells.

Feline Calicivirus Antigen

NAT41595-100 0.1
EUR 391.66
Description: Feline Calicivirus produced in FC 3TG cells.

Helicobacter Pylori Antigen

NAT41603-100 0.1
EUR 391.66
Description: Bacteria are cultured on solid medium, harvested, washed and solubilised. The antigen is partially purified by detergent extraction and centrifugation.

Helicobacter Pylori Antigen

NAT41603-500 0.5
EUR 1176.24
Description: Bacteria are cultured on solid medium, harvested, washed and solubilised. The antigen is partially purified by detergent extraction and centrifugation.

Campylobacter Jejuni Antigen

NAT41600-100 0.1
EUR 391.66
Description: Campylobacter jejuni is cultured on solid medium. This antigen is a partially purified detergent extract of the membrane fraction. The main component is an outer membrane protein, approximately 45 kDa in SDS-PAGE.

Campylobacter Jejuni Antigen

NAT41600-500 0.5
EUR 1176.24
Description: Campylobacter jejuni is cultured on solid medium. This antigen is a partially purified detergent extract of the membrane fraction. The main component is an outer membrane protein, approximately 45 kDa in SDS-PAGE.

Chlamydia Trachomatis Antigen

CT022-1000 1.0
EUR 378.9
Description: Chlamydia trachomatis antigens from clarified cell lysate.

Neisseria Gonorrhoeae Antigen

NG01-1000 1.0
EUR 378.9
Description: Homogenised lysate of pure bacteria.

Mycoplasma Pneumoniae Antigen

MP901-1000 1.0
EUR 1010.39
Description: Mycoplasma pneumoniae whole organisms that have been purified and detergent treated to enrich antigenic proteins and decrease background.

Mycoplasma Pneumoniae Antigen

MP901-200 0.2
EUR 270.46
Description: Mycoplasma pneumoniae whole organisms that have been purified and detergent treated to enrich antigenic proteins and decrease background.

Echovirus Antigen, Recombinant

REC31776-100 0.1
EUR 276.84
Description: Proprietary recombinant antigen expressed in E. coli and purified by chromatography. Individually pooled antigens shown to react with QC serum panel (multiple negative, borderline and positive sera) within defined reactivity range in Coxsackie-/Echovirus

Echovirus Antigen, Recombinant

REC31776-500 0.5
EUR 1043.56
Description: Proprietary recombinant antigen expressed in E. coli and purified by chromatography. Individually pooled antigens shown to react with QC serum panel (multiple negative, borderline and positive sera) within defined reactivity range in Coxsackie-/Echovirus

Trichomonas Vaginalis Antigen

TV01-1000 1.0
EUR 421
Description: Washed & lysed suspension of whole protozoa

Echinococcus Granulosus Antigen

NAT41602-100 0.1
EUR 391.66
Description: Echinococcus granulosus material is derived from bovine hydatid cyst as sterile filtered cyst fluid.

Echinococcus Granulosus Antigen

NAT41602-500 0.5
EUR 1176.24
Description: Echinococcus granulosus material is derived from bovine hydatid cyst as sterile filtered cyst fluid.

Enterovirus Antigen, Recombinant

REC31772-100 0.1
EUR 276.84
Description: Proprietary recombinant antigen expressed in E. coli and purified by chromatography. Individually pooled antigens shown to react with QC serum panel (multiple negative, borderline and positive sera) within defined reactivity range in Coxsackie-/Echovirus IgA, IgG and IgM ELISA.

Enterovirus Antigen, Recombinant

REC31772-500 0.5
EUR 1043.56
Description: Proprietary recombinant antigen expressed in E. coli and purified by chromatography. Individually pooled antigens shown to react with QC serum panel (multiple negative, borderline and positive sera) within defined reactivity range in Coxsackie-/Echovirus IgA, IgG and IgM ELISA.

Astrovirus Antigen (Type 1)

AS02-1000 1.0
EUR 1654.65
Description: A concentrated source of Astrovirus particles and Astrovirus proteins from a lysate of host cells.

Astrovirus Antigen (Type 1)

AS02-200 0.2
EUR 442.69
Description: A concentrated source of Astrovirus particles and Astrovirus proteins from a lysate of host cells.

Yersinia pestis V antigen

REC32028-100 0.1
EUR 491.53
Description: Yersinia pestis V antigen (LcrV antigen, capsule protein fraction 1, type III secretion system needle tip protein). The protein is produced as an N-terminal GST fusion, with GST being cleaved by thrombin and is not present in the final product.

Yersinia pestis V antigen

REC32028-500 0.5
EUR 2421.37
Description: Yersinia pestis V antigen (LcrV antigen, capsule protein fraction 1, type III secretion system needle tip protein). The protein is produced as an N-terminal GST fusion, with GST being cleaved by thrombin and is not present in the final product.

Cytomegalovirus Purified Antigen

CMV-HP-100 0.1
EUR 318.94
Description: A concentrated source of human Cytomegalovirus particles purified by sucrose gradient ultracentrifugation.

Cytomegalovirus Purified Antigen

CMV-HP-1000 1.0
EUR 2096.06
Description: A concentrated source of human Cytomegalovirus particles purified by sucrose gradient ultracentrifugation.

Cytomegalovirus Purified Antigen

CMV-HP-500 0.5
EUR 1279.58
Description: A concentrated source of human Cytomegalovirus particles purified by sucrose gradient ultracentrifugation.

Canine Herpes Virus Antigen

NAT41592-100 0.1
EUR 391.66
Description: Canine Herpes virus, produced in MDCK cells.

Canine Adenovirus 1 Antigen

NAT41587-100 0.1
EUR 391.66
Description: Canine Adenovirus Type 1, produced in A-72 cells.

Canine Adenovirus 2 Antigen

NAT41588-100 0.1
EUR 391.66
Description: Canine Adenovirus Type 2, produced in A-72 cells.

Canine Distemper Virus Antigen

NAT41591-100 0.1
EUR 391.66
Description: Canine Distemper virus, produced in SL-29 cells.

Norovirus GII.4 VP1 Antigen

REC31620-100 0.1
EUR 302.36
Description: Recombinant Norovirus GII.4 VP1 antigen produced in 293 human cells.

Norovirus GII.4 VP1 Antigen

REC31620-1000 1.0
EUR 1830.71
Description: Recombinant Norovirus GII.4 VP1 antigen produced in 293 human cells.

Norovirus GII.4 VP1 Antigen

REC31620-500 0.5
EUR 1066.53
Description: Recombinant Norovirus GII.4 VP1 antigen produced in 293 human cells.

Canine Parainfluenza Virus Antigen

NAT41593-100 0.1
EUR 391.66
Description: Canine Parainfluenza virus antigen, produced in MDCK cells.

Feline Panleukopenia Virus Antigen

NAT41597-100 0.1
EUR 391.66
Description: Feline Panleukopenia Virus (FPLV; feline parvovirus) antigen, produced in CRFK cells.

Cytomegalovirus Cell Lysate Antigen

CMV-CL-100 0.1
EUR 223.26
Description: A clarified cell lysate containing a mix of CMV antigens from all stages of the replication life cycle.

Cytomegalovirus Cell Lysate Antigen

CMV-CL-1000 1.0
EUR 1422.47
Description: A clarified cell lysate containing a mix of CMV antigens from all stages of the replication life cycle.

Herpes Simplex Virus 1 Antigen

HS105-1000 1.0
EUR 1178.79
Description: HSV-1 particles from a cell lysate are purified by sucrose gradient ultracentrifugation.

Herpes Simplex Virus 1 Antigen

HS105-200 0.2
EUR 294.7
Description: HSV-1 particles from a cell lysate are purified by sucrose gradient ultracentrifugation.

Herpes Simplex Virus 2 Antigen

HS205-1000 1.0
EUR 1178.79
Description: HSV-2 particles from a cell lysate are purified by sucrose gradient ultracentrifugation.

Herpes Simplex Virus 2 Antigen

HS205-200 0.2
EUR 294.7
Description: HSV-2 particles from a cell lysate are purified by sucrose gradient ultracentrifugation.

Feline Viral Rhinotracheitis Antigen

NAT41598-100 0.1
EUR 391.66
Description: Feline Viral Rhinotracheitis (FVR; feline herpes virus, FHV-1) antigen, produced in CRFK cells.

Ross River Virus Recombinant Antigen

REC31969-100 0.1
EUR 757.8
Description: Recombinant Ross River virus antigen expressed in HEK293 cells as virus-like particles and purified by sucrose density gradients and precipitation. Virus-like particles were then solubilized in PBS containing 0.2% SDS to prevent aggregation of particles. The preparation is not particulate. Antigens in the preparation include Envelope proteins 1 and 2 and Nucleoprotein.

Ross River Virus Recombinant Antigen

REC31969-500 0.5
EUR 2844.92
Description: Recombinant Ross River virus antigen expressed in HEK293 cells as virus-like particles and purified by sucrose density gradients and precipitation. Virus-like particles were then solubilized in PBS containing 0.2% SDS to prevent aggregation of particles. The preparation is not particulate. Antigens in the preparation include Envelope proteins 1 and 2 and Nucleoprotein.

Canine Adenovirus 1 and 2 Antigen

NAT41589-100 0.1
EUR 391.66
Description: A mixture of Canine Adenovirus Type 1 and Type 2, produced in A-72 cells.

Hepatitis B Virus E Antigen (HBeAg)

REC31677-100 0.1
EUR 456.72
Description: Recombinant Hepititis B Virus E Protein (HBeAg).

Hepatitis B Virus E Antigen (HBeAg)

REC31677-500 0.5
EUR 1941.06
Description: Recombinant Hepititis B Virus E Protein (HBeAg).

Hepatitis B Virus Core Antigen (HBcAg)

REC31689-100 0.1
EUR 456.72
Description: Recombinant Hepititis B Virus Core Protein (HBcAg).

Hepatitis B Virus Core Antigen (HBcAg)

REC31689-500 0.5
EUR 1370.16
Description: Recombinant Hepititis B Virus Core Protein (HBcAg).

Hepatitis C Virus Core Antigen (HCcAg)

REC31693-100 0.1
EUR 484.79
Description: Recombinant Hepatitis C Virus core protein is produced in E. coli and fused with a His-tag.

Hepatitis C Virus Core Antigen (HCcAg)

REC31693-500 0.5
EUR 1455.64
Description: Recombinant Hepatitis C Virus core protein is produced in E. coli and fused with a His-tag.

Herpes Simplex Virus 1 Lysate Antigen

HS104-1000 1.0
EUR 270.46
Description: A high concentration of HSV-1 particles and proteins from a clarified cell lysate.

Herpes Simplex Virus 2 Lysate Antigen

HS204-1000 1.0
EUR 270.46
Description: A high concentration of HSV-2 particles and proteins from a clarified cell lysate.

Feline Infectious Peritonitis Virus Antigen

NAT41596-100 0.1
EUR 391.66
Description: Feline Infectious Peritonitis virus (FIPV; feline coronavirus) antigen, produced in CRFK cells.

Legionella pneumophila antigen (native extract)

NAT41580-100 0.1
EUR 391.66
Description: Inactivated Legionella pneumophila antigen from culture.

Leptospira Biflexa Antigen (Strain Patoc 1)

NAT41582-100 0.1
EUR 391.66
Description: Inactivated Leptospira biflexa antigen (Strain Patoc 1) from broth culture.

Leptospira Biflexa Antigen (Strain Patoc 1)

NAT41582-500 0.5
EUR 1176.24
Description: Inactivated Leptospira biflexa antigen (Strain Patoc 1) from broth culture.

Streptococcus Pneumoniae Antigen, Native Extract

NAT41604-100 0.1
EUR 391.66
Description: Inactivated Streptococcus pneumoniae antigen from culture.

Mouse Anti-Giardia Monoclonal Antibody (E4)

MAB12477-100 0.1
EUR 395.48
Description: This antibody recognises the Cyst-Wall-Protein-1 (CWP1) antigen on the surface of Giardia cysts.

Mouse Anti-Giardia Monoclonal Antibody (E4)

MAB12477-500 0.5
EUR 1678.89
Description: This antibody recognises the Cyst-Wall-Protein-1 (CWP1) antigen on the surface of Giardia cysts.

Mouse Anti-Giardia Monoclonal Antibody (E11)

MAB12478-100 0.1
EUR 395.48
Description: This antibody recognises the Cyst-Wall-Protein-1 (CWP1) antigen on the surface of Giardia cysts.

Mouse Anti-Giardia Monoclonal Antibody (E11)

MAB12478-500 0.5
EUR 1678.89
Description: This antibody recognises the Cyst-Wall-Protein-1 (CWP1) antigen on the surface of Giardia cysts.

Mouse Anti-Giardia Monoclonal Antibody (G203)

MAB12479-100 0.1
EUR 447.93
Description: This antibody recognises the Cyst-Wall-Protein-1 (CWP1) antigen on the surface of Giardia cysts.

Mouse Anti-Giardia Monoclonal Antibody (G203)

MAB12479-500 0.5
EUR 1678.89
Description: This antibody recognises the Cyst-Wall-Protein-1 (CWP1) antigen on the surface of Giardia cysts.

MOUSE ANTI MOUSE NK-1.1 ANTIGEN

MBS212065-025mg 0.25mg
EUR 500

MOUSE ANTI MOUSE NK-1.1 ANTIGEN

MBS212065-5x025mg 5x0.25mg
EUR 2070

Yersinia pestis chain B F1 capsule antigen, C-terminal His-tag

REC32027-100 0.1
EUR 491.53
Description: Yersinia pestis chain B F1 capsule antigen (Antig_Caf1)

Yersinia pestis chain B F1 capsule antigen, C-terminal His-tag

REC32027-500 0.5
EUR 2421.37
Description: Yersinia pestis chain B F1 capsule antigen (Antig_Caf1)

Mouse Anti-Giardia Lamblia Trophozoite Antibody (G18)

MAB12153-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for Giardia lamblia trophoziote protein (clone G18)

Mouse Anti-Giardia Lamblia Trophozoite Antibody (G22)

MAB12154-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for Giardia lamblia trophoziote protein (clone G22)

Mouse Anti-Hepatitis D Antigen (Delta Virus Antigen)

MBS6506734-1mg 1mg
EUR 785

Mouse Anti-Hepatitis D Antigen (Delta Virus Antigen)

MBS6506734-5x1mg 5x1mg
EUR 3305

MECA-79 Antibody / Peripheral Node Addressin / PNAd

V8344-100UG 100 ug
EUR 424.15
Description: MECA-79 recognizes a carbohydrate epitope shared with a group of sulfation decorated sialomucins, including sulfated ligands for CD62L (CD34, GlyCAM-1, Sgp200, and a subset of MAdCAM-1). This set antigens has been referred to as peripheral node addressin (PNAd) with the molecular mass 50-250 kD. It has been identified that GlcNAc-6-SO4 sulfation contributes to MECA-79 binding and the core 1 beta1,3-N-acetylglucosaminyltransferase is required for the generation of the MECA-79 epitope. MECA-79 is expressed on high endothelial venules (HEV) of lymphoid tissues, chronic inflamed tissues and rheumatoid synovia. The interaction of PNAd with CD62L receptor is involved in tethering and rolling of lymphocytes along HEV in lymphoid tissues. MECA-79 antibody reacts with Mouse, human and many other species PNAd and blocks L-selectin-dependent lymphocyte adhesion in vitro and in vivo.

MECA-79 Antibody / Peripheral Node Addressin / PNAd

V8344-20UG 20 ug
EUR 186.15
Description: MECA-79 recognizes a carbohydrate epitope shared with a group of sulfation decorated sialomucins, including sulfated ligands for CD62L (CD34, GlyCAM-1, Sgp200, and a subset of MAdCAM-1). This set antigens has been referred to as peripheral node addressin (PNAd) with the molecular mass 50-250 kD. It has been identified that GlcNAc-6-SO4 sulfation contributes to MECA-79 binding and the core 1 beta1,3-N-acetylglucosaminyltransferase is required for the generation of the MECA-79 epitope. MECA-79 is expressed on high endothelial venules (HEV) of lymphoid tissues, chronic inflamed tissues and rheumatoid synovia. The interaction of PNAd with CD62L receptor is involved in tethering and rolling of lymphocytes along HEV in lymphoid tissues. MECA-79 antibody reacts with Mouse, human and many other species PNAd and blocks L-selectin-dependent lymphocyte adhesion in vitro and in vivo.

MECA-79 Antibody / Peripheral Node Addressin / PNAd

V8344SAF-100UG 100 ug
EUR 424.15
Description: MECA-79 recognizes a carbohydrate epitope shared with a group of sulfation decorated sialomucins, including sulfated ligands for CD62L (CD34, GlyCAM-1, Sgp200, and a subset of MAdCAM-1). This set antigens has been referred to as peripheral node addressin (PNAd) with the molecular mass 50-250 kD. It has been identified that GlcNAc-6-SO4 sulfation contributes to MECA-79 binding and the core 1 beta1,3-N-acetylglucosaminyltransferase is required for the generation of the MECA-79 epitope. MECA-79 is expressed on high endothelial venules (HEV) of lymphoid tissues, chronic inflamed tissues and rheumatoid synovia. The interaction of PNAd with CD62L receptor is involved in tethering and rolling of lymphocytes along HEV in lymphoid tissues. MECA-79 antibody reacts with Mouse, human and many other species PNAd and blocks L-selectin-dependent lymphocyte adhesion in vitro and in vivo.

Anti-La Antigen Mouse mAb

E2201300 100ul
EUR 225
Description: Available in various conjugation types.

Anti-La Antigen Mouse mAb

MBS8533223-01mL 0.1mL
EUR 305

Anti-La Antigen Mouse mAb

MBS8533223-01mLAF405L 0.1mL(AF405L)
EUR 565

Anti-La Antigen Mouse mAb

MBS8533223-01mLAF405S 0.1mL(AF405S)
EUR 565

Anti-La Antigen Mouse mAb

MBS8533223-01mLAF610 0.1mL(AF610)
EUR 565

Anti-La Antigen Mouse mAb

MBS8533223-01mLAF635 0.1mL(AF635)
EUR 565

Anti-La Antigen Mouse mAb

MBS475587-01mL 0.1mL
EUR 450

Anti-La Antigen Mouse mAb

MBS475587-5x01mL 5x0.1mL
EUR 1540

Mouse anti Carcinoma ass. Antigen

MBS570279-01mg 0.1mg
EUR 515

Mouse anti Carcinoma ass. Antigen

MBS570279-5x01mg 5x0.1mg
EUR 2165

MOUSE ANTI HUMAN NUCLEAR ANTIGEN

MBS211180-01mL 0.1mL
EUR 605

MOUSE ANTI HUMAN NUCLEAR ANTIGEN

MBS211180-5x01mL 5x0.1mL
EUR 2555

PLVAP rat monoclonal antibody, clone MECA-32, Biotin

AM05595BT-N 100 µg Ask for price

PLVAP rat monoclonal antibody, clone MECA-32, Purified

AM05595PU-L 250 µg Ask for price

PLVAP rat monoclonal antibody, clone MECA-32, Purified

AM05595PU-N 100 µg Ask for price

PLVAP rat monoclonal antibody, clone MECA-32, Purified

AM05595PU-T 25 µg Ask for price

MOUSE ANTI ANTHRAX PROTECTIVE ANTIGEN

MBS214545-02mg 0.2mg
EUR 515

MOUSE ANTI ANTHRAX PROTECTIVE ANTIGEN

MBS214545-5x02mg 5x0.2mg
EUR 2145

Mouse Anti-Adenovirus Antibody (A68)

MAB12508-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for Adenovirus (clone A68).

Mouse Anti-Adenovirus Antibody (A68)

MAB12508-500 0.5
EUR 964.47
Description: Mouse monoclonal antibody specific for Adenovirus (clone A68).

Mouse Anti-Adenovirus Antibody (A93)

MAB12509-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for Adenovirus (clone A93).

Mouse Anti-Adenovirus Antibody (A93)

MAB12509-500 0.5
EUR 964.47
Description: Mouse monoclonal antibody specific for Adenovirus (clone A93).

Mouse anti Melanoma Associated Antigen

MBS570200-01mg 0.1mg
EUR 515

Mouse anti Melanoma Associated Antigen

MBS570200-5x01mg 5x0.1mg
EUR 2165

Mouse anti Melanoma Associated Antigen

MBS570274-01mg 0.1mg
EUR 515

Mouse anti Melanoma Associated Antigen

MBS570274-5x01mg 5x0.1mg
EUR 2165

Mouse Anti-Astrovirus Antibody (AT54)

MAB12138-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for Astrovirus (clone AT54)

Mouse Anti-Adenovirus Antibody (A114)

MAB12510-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for Adenovirus (clone A114).

Mouse Anti-Adenovirus Antibody (A114)

MAB12510-500 0.5
EUR 964.47
Description: Mouse monoclonal antibody specific for Adenovirus (clone A114).

Mouse Anti-Adenovirus Antibody (A115)

MAB12511-100 0.1
EUR 275.56
Description: Mouse monoclonal antibody specific for Adenovirus (clone A115).

Mouse Anti-Adenovirus Antibody (A115)

MAB12511-500 0.5
EUR 964.47
Description: Mouse monoclonal antibody specific for Adenovirus (clone A115).

MECA-79(MECA-79), 0.2mg/mL

BNUB1599-100 1uL
EUR 225
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

MECA-79(MECA-79), 0.2mg/mL

BNUB1599-500 1uL
EUR 485
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application

MECA-79(MECA-79), 1mg/mL

BNUM1599-50 1uL
EUR 396
Description: Primary and secondary antibodies for multiple methodologyimmunostaining detection application
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